Evidence map›Paper›PMID 27013438›Full record

ArticleVaccine2016

Risk factors for measles infection in 0-7 month old children in China after the 2010 nationwide measles campaign: A multi-site case-control study, 2012-2013.

Chao Ma, Christopher J Gregory, Lixin Hao, Kathleen A Wannemuehler, Qiru Su, Zhijie An, Linda Quick, Lance Rodewald, Fubao Ma, Rui Yan and 9 more

Abstract read
In one paragraph

Article in Vaccine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Notifiable Respiratory Infectious Diseases in China: A Spatial-Temporal Epidemiology Analysis.International journal of environmental research and public health · 2020
    Article
  4. Article
  5. Global trends in measles publications.The Pan African medical journal · 2020
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Chao MaNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Christopher J GregoryGlobal Immunization Division, Centers for Disease Control and Prevention, United States.
Lixin HaoNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Kathleen A WannemuehlerGlobal Immunization Division, Centers for Disease Control and Prevention, United States.
Qiru SuNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhijie AnNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Linda QuickGlobal Immunization Division, Centers for Disease Control and Prevention, United States.
Lance RodewaldExpanded Program on Immunization, World Health Organization Office in China, Beijing, China.
Fubao MaJiangsu Provincial Center for Disease Control and Prevention, Jiangsu Province, China.
Rui YanZhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang Province, China.
Lizhi SongShandong Provincial Center for Disease Control and Prevention, Shangdong Province, China.
Yanyang ZhangHenan Provincial Center for Disease Control and Prevention, Henan Province, China.
Yi KongYunnan Provincial Center for Disease Control and Prevention, Yunnan Province, China.
Xiaoshu ZhangGansu Provincial Center for Disease Control and Prevention, Gansu Province, China.
Huaqing WangNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Li LiNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Lisa CairnsGlobal Immunization Division, Centers for Disease Control and Prevention, United States.
Ning WangNational Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Huiming LuoNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China. Electronic address: luohm@chinacdc.cn.

Funding

Intramural CDC HHS CC999999World Health Organization 001
6 · The paper itself

Abstract

introductionEndemic measles persists in China, despite >95% reported coverage of two measles-containing vaccine doses and nationwide campaign that vaccinated more than 100 million children in 2010. We performed a case-control study in six Chinese provinces during January 2012 through June 2013 to identify risk factors for measles infection among children aged 0-7 months.

methodsChildren with laboratory-confirmed measles were neighborhood matched with three controls. We interviewed parents of case and control infants on potential risk factors for measles. Adjusted matched odds ratios (mOR) and 95% confidence intervals (CIs) were calculated by multivariable conditional logistic modeling. We calculated attributable fractions for risk factors that could be interpreted as causal.

resultsEight hundred thirty cases and 2303 controls were enrolled. In multivariable analysis, male sex (mOR 1.6 [1.3, 2.0]), age 5-7 months (mOR 3.9 [3.0, 5.1]), migration between counties (mOR 2.3 [1.6, 3.4]), outpatient hospital visits (mOR 9.4 [6.6, 13.3]) and inpatient hospitalization (mOR 107.1 [48.8, 235.1]) were significant risk factors. The calculated attributable fractions for hospital visits was 43.1% (95% CI: 40.1, 47.5%) adjusted for age, sex and migration.

conclusionsHospital visitation was the largest risk factor for measles infection in infants. Improved hospital infection control practices would accelerate measles elimination in China.

Indexed as

Case-Control StudiesChinaFemaleHumansInfantInfant, NewbornMaleMeaslesRisk FactorsCase–control studyChinaMeaslesMeasles eliminationPopulation immunityRisk factors

Identifiers

PMID27013438
PMCPMC6524948

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.