Evidence map›Paper›PMID 27013288›Full record

ReviewMaturitas2016

A biopsychosocial approach to women's sexual function and dysfunction at midlife: A narrative review.

Holly N Thomas, Rebecca C Thurston

Open access · greenAbstract readReview
In one paragraph

Review in Maturitas, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 6 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 6 syntheses or guidelines pooled it, 212 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Let's talk about sex: consensus guidelines of the GINECOR working group of the Spanish Society of Radiation Oncology: clinical recommendations after pelvic radiotherapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Guideline
  4. Sexual Dysfunction in Patients with Chronic Non-Genital Physical Disease: An Umbrella Review.International journal of environmental research and public health · 2025
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Effect ofInternational journal of clinical practice · 2023
    Trial
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  11. Trial
  12. Article
  13. Article
  14. Women's experiences of sexuality during menopausal transition: An interview study.European journal of obstetrics & gynecology and reproductive biology: X · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Holly N ThomasUniversity of Pittsburgh, Department of Medicine, United States. Electronic address: thomashn@upmc.edu.
Rebecca C ThurstonUniversity of Pittsburgh, Department of Psychiatry, United States.
University of Pittsburgh · US

Funding

Patient-Centered Outcomes Research (PCOR) Scholars ProgramK12HS022989 · AHRQ · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAPOOR, WISHWA N · 2014 to 2018
$3.9M
Interdisciplinary Mentoring and Research in Womens Cardiovascular HealthK24HL123565 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI THURSTON, REBECCA C · 2014 to 2023
$1.0M
AHRQ HHS K12 HS022989AHRQ HHS K12HS022989NHLBI NIH HHS K24 HL123565PHS HHS K24123565
6 · The paper itself

Abstract

A satisfying sex life is an important component of overall well-being, but sexual dysfunction is common, especially in midlife women. The aim of this review is (a) to define sexual function and dysfunction, (b) to present theoretical models of female sexual response, (c) to examine longitudinal studies of how sexual function changes during midlife, and (d) to review treatment options. Four types of female sexual dysfunction are currently recognized: Female Orgasmic Disorder, Female Sexual Interest/Arousal Disorder, Genito-Pelvic Pain/Penetration Disorder, and Substance/Medication-Induced Sexual Dysfunction. However, optimal sexual function transcends the simple absence of dysfunction. A biopsychosocial approach that simultaneously considers physical, psychological, sociocultural, and interpersonal factors is necessary to guide research and clinical care regarding women's sexual function. Most longitudinal studies reveal an association between advancing menopause status and worsening sexual function. Psychosocial variables, such as availability of a partner, relationship quality, and psychological functioning, also play an integral role. Future directions for research should include deepening our understanding of how sexual function changes with aging and developing safe and effective approaches to optimizing women's sexual function with aging. Overall, holistic, biopsychosocial approaches to women's sexual function are necessary to fully understand and treat this key component of midlife women's well-being.

Indexed as

AgingFemaleHumansLongitudinal StudiesMenopauseMiddle AgedModels, TheoreticalSexual BehaviorSexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalAgingMenopauseMidlifeSexual dysfunctionSexual functionWomen’s health

Identifiers

PMID27013288
PMCPMC4808247
OpenAlexW2286057388

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.