Evidence map›Paper›PMID 27013232›Full record

Observational studyJournal of neurointerventional surgery2017

Medicare expenditures for elderly patients undergoing surgical clipping or endovascular intervention for unruptured cerebral aneurysms.

Kimon Bekelis, Dan Gottlieb, Yin Su, Nicos Labropoulos, George Bovis, Michael T Lawton, Todd A MacKenzie

Abstract readObservational Study
In one paragraph

Observational study in Journal of neurointerventional surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Kimon BekelisSection of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
Dan GottliebThe Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, New Hampshire, USA.
Yin SuThe Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, New Hampshire, USA.
Nicos LabropoulosDepartment of Radiology, Stony Brook University Medical Center, Stony Brook, New York, USA.
George BovisDepartment of Neurosurgery, Rush University Medical Center, Chicago, Illinois, USA.
Michael T LawtonDepartment of Neurosurgery, University of California, San Francisco Medical Center, San Francisco, California, USA.
Todd A MacKenzieDepartment of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Dartmouth Institute for Health Policy and Clinical Practice · USDartmouth–Hitchcock Medical Center · USRush University Medical Center · USStony Brook University Hospital · USUniversity of California San Francisco Medical Center · US

Funding

UNDERSTANDING AND IMPROVING EPISODE-BASED HOSPITAL CAREP01AG019783 · NIA · DARTMOUTH COLLEGE · PI Alistair James O'MALLEY · 2001 to 2026
$52.9M
SYNERGY: The Dartmouth Center for clinical and Translational ScienceUL1TR001086 · NCATS · DARTMOUTH COLLEGE · PI GREEN, ALAN I · 2013 to 2017
$18.3M
Technology Diffusion, Health Outcomes, and Healthcare ExpendituresU01AG046830 · NIA · DARTMOUTH COLLEGE · PI SKINNER, JONATHAN S · 2013 to 2017
$4.5M
NCATS NIH HHS UL1 TR001086NIA NIH HHS P01 AG019783NIA NIH HHS U01 AG046830
6 · The paper itself

Abstract

backgroundThe cost difference between the two treatment options (surgical clipping and endovascular therapy) for unruptured cerebral aneurysms remains an issue of debate. We investigated the association between treatment method for unruptured cerebral aneurysms and Medicare expenditures in elderly patients.

methodsWe performed a cohort study of 100% Medicare fee-for-service claims data for elderly patients who underwent treatment for unruptured cerebral aneurysms from 2007 to 2012. In order to control for measured confounding we used multivariable regression analysis with mixed effects to account for clustering at the Hospital Referral Region (HRR) level. An instrumental variable (regional rates of endovascular treatment) analysis was used to control for unmeasured confounding by creating pseudo-randomization on the treatment method.

resultsDuring the study period 8705 patients underwent treatment for unruptured cerebral aneurysms and met the inclusion criteria. Of these, 2585 (29.7%) had surgical clipping and 6120 (70.3%) had endovascular treatment. The median total Medicare expenditures in the first year after the admission for the procedure were $46 800 (IQR $31 000-$74 400) for surgical clipping and $48 100 (IQR $34 500-$73 900) for endovascular therapy. When we adjusted for unmeasured confounders, using an instrumental variable analysis, clipping was associated with increased 7-day Medicare expenditures by $3527 (95% CI $972 to $5736) and increased 1-year Medicare expenditures by $15 984 (95% CI $9017 to $22 951).

conclusionsIn a cohort of Medicare patients, after controlling for unmeasured confounding, we demonstrated that surgical clipping of unruptured cerebral aneurysms was associated with increased 1-year expenditures compared with endovascular treatment.

Indexed as

Health ExpendituresAgedCohort StudiesEndovascular ProceduresFemaleHospitalizationHumansIntracranial AneurysmMaleMedicareMiddle AgedSurgical InstrumentsTreatment OutcomeUnited StatesAneurysmCoil

Identifiers

PMID27013232
PMCPMC5035560
OpenAlexW2311671548

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.