Evidence map›Paper›PMID 27012848›Full record

Trial reportJournal of behavioral medicine2016

Randomized trial of a phone- and web-based weight loss program for women at elevated breast cancer risk: the HELP study.

Lisa Cadmus-Bertram, Sandahl H Nelson, Sheri Hartman, Ruth E Patterson, Barbara A Parker, John P Pierce

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of behavioral medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. A systematic review of inequalities in the uptake of, adherence to, and effectiveness of behavioral weight management interventions in adults.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lisa Cadmus-BertramDepartment of Kinesiology, University of Wisconsin - Madison, 2000 Observatory Drive, Madison, WI, 53706, USA. lisa.bertram@wisc.edu.
Sandahl H NelsonDepartment of Family Medicine and Public Health, Moores UCSD Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA, 92093-0901, USA.
Sheri HartmanDepartment of Family Medicine and Public Health, Moores UCSD Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA, 92093-0901, USA.
Ruth E PattersonDepartment of Family Medicine and Public Health, Moores UCSD Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA, 92093-0901, USA.
Barbara A ParkerDepartment of Medicine, Moores UCSD Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA, 92093-0901, USA.
John P PierceDepartment of Family Medicine and Public Health, Moores UCSD Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA, 92093-0901, USA.
University of California, San Diego · USUniversity of Wisconsin–Madison · US

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jesse Nodora · 1985 to 2026
$124.9M
Physical Activity and neuropsychological outcomes in a cancer populationK07CA181323 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HARTMAN, SHERI J · 2014 to 2018
$852k
Sedentary Behavior and Breast Cancer: Interventions and BiomarkersK07CA178870 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI CADMUSBERTRAM, LISA ANNE · 2014 to 2017
$547k
NCI NIH HHS K07 CA178870NCI NIH HHS K07 CA181323NCI NIH HHS P30 CA023100
6 · The paper itself

Abstract

Excess weight and physical inactivity are modifiable risk factors for breast cancer. Behavioral intervention is particularly important among women with an elevated risk profile. This trial tested an intervention that trained women to use a self-monitoring website to increase activity and lose weight. Women with BMI ≥27.5 kg/m(2) at elevated breast cancer risk were randomized to the intervention (N = 71) or usual care (N = 34). The intervention group received telephone-based coaching and used web-based self-monitoring tools. At 6 months, significant weight loss was observed in the intervention group (4.7 % loss from starting weight; SD = 4.7 %) relative to usual care (0.4 % gain; SD = 3.0 %) (p < 0.0001). By 12 months, the intervention group had lost 3.7 % of weight (SD = 5.4 %), compared to 1.3 % (SD = 4.2) for usual care (p = 0.003). At 12 months, accelerometer-measured moderate-to-vigorous physical activity increased by 12 min/day (SD = 24) compared to no change in usual care (p = 0.04. In summary, this web- and phone-based approach produced modest but significant improvements in weight and physical activity for women at elevated breast cancer risk.

Indexed as

InternetTelephoneAdultAgedBody WeightBreast NeoplasmsDisease SusceptibilityExerciseFemaleHumansMiddle AgedRisk FactorsTreatment OutcomeWeight LossWeight Reduction ProgramsBreast cancerInternetPhysical activitySelf-monitoringTechnologyWeight loss

Identifiers

PMID27012848
PMCPMC4945463
OpenAlexW2316692684

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.