Evidence map›Paper›PMID 27012806›Full record

ArticleAlcoholism, clinical and experimental research2016

Dietary Nutrient Intake in School-Aged Children With Heavy Prenatal Alcohol Exposure.

Tanya T Nguyen, Rashmi D Risbud, Christina D Chambers, Jennifer D Thomas

Open access · greenAbstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Tanya T NguyenVA San Diego Healthcare System , Mental Illness Research, Education, and Clinical Center (MIRECC), San Diego, California.
Rashmi D RisbudCenter for Behavioral Teratology , Department of Psychology, San Diego State University, San Diego, California.
Christina D ChambersDivision of Dysmorphology and Teratology , Department of Pediatrics, University of California, San Diego, San Diego, California.
Jennifer D ThomasCenter for Behavioral Teratology , Department of Psychology, San Diego State University, San Diego, California.
San Diego State University · USMental Illness Research, Education and Clinical Centers · USUniversity of California, San Diego · US

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ian Michael Carroll · 1999 to 2026
$31.6M
Fetal Alcohol Effects and Choline InterventionR01AA012446 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI THOMAS, JENNIFER D · 2001 to 2015
$3.8M
Choline Intervention in Children with Fetal Alcohol Spectrum DisordersF31AA021630 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI NGUYEN, TANYA T · 2012 to 2014
$94k
NIAAA NIH HHS F31 AA021630NIAAA NIH HHS R01 AA012446NIDDK NIH HHS P30 DK056350
6 · The paper itself

Abstract

backgroundNutrition is an important factor that affects brain development. Nutritional deficiencies can exacerbate alcohol's damaging effects. Conversely, nutritional supplementation can serve a protective role against alcohol damage and may prove to be a worthwhile intervention strategy. This study investigated dietary intake in school-aged children with heavy prenatal alcohol exposure to understand their nutritional status, compared to a national sample of typically developing children and Dietary Reference Intakes.

methodsDietary intake data were collected from children with confirmed histories of heavy prenatal alcohol exposure (5 to 10 years, n = 55) using the Automated Self-Administered 24-Hour Dietary Recall (ASA24). Observed nutrient levels were compared to the Dietary Reference Intakes to evaluate adequacy of nutrient intake as well as to national averages for same-aged children (What We Eat in America, NHANES 2007-2008).

resultsAlcohol-exposed children exhibited poorer nutritional status compared to the typically developing NHANES sample, consuming lower levels of protein, omega-3 fatty acids, magnesium, potassium, zinc, vitamins C and K, niacin, and choline. Moreover, their diets did not meet Recommended Dietary Allowance or Adequate Intake for dietary fiber, potassium, vitamins E and K, omega-3 fatty acids, and choline.

conclusionsThe present findings are consistent with prior studies investigating nutritional intake in preschoolers with FASD, indicating that these children are vulnerable to nutritional inadequacies. Moreover, data suggest a specific profile of dietary intake in this population. As several nutrients are important for cognitive development, targeted interventions in clinical populations might be effective in boosting outcomes. Thus, further clinical investigation into the role of nutrition in improving cognitive outcomes is warranted.

Indexed as

DietNutritional StatusCase-Control StudiesChildChild, PreschoolEnergy IntakeFemaleFetal Alcohol Spectrum DisordersHumansMaleNutrition SurveysPregnancyDietary IntakeFetal Alcohol Spectrum DisordersFetal Alcohol SyndromeNutritionPrenatal Alcohol Exposure

Identifiers

PMID27012806
PMCPMC4844832
OpenAlexW2308360981

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.