Evidence map›Paper›PMID 27012372›Full record

ArticleInfluenza and other respiratory viruses2016

Viral etiology of severe acute respiratory infections in hospitalized children in Cameroon, 2011-2013.

Sebastien Kenmoe, Patrice Tchendjou, Marie-Astrid Vernet, Suzie Moyo-Tetang, Tatiana Mossus, Mohamadou Njankouo-Ripa, Angeladine Kenne, Véronique Penlap Beng, Astrid Vabret, Richard Njouom

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 7 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 7 syntheses or guidelines pooled it, 91 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Sebastien KenmoeCentre Pasteur of Cameroon, International Network of Pasteur Institutes, Yaounde, Cameroon.
Patrice TchendjouCentre Pasteur of Cameroon, International Network of Pasteur Institutes, Yaounde, Cameroon.
Marie-Astrid VernetCentre Pasteur of Cameroon, International Network of Pasteur Institutes, Yaounde, Cameroon.
Suzie Moyo-TetangEssos Hospital Center, Yaounde, Cameroon.
Tatiana MossusCentre Pasteur of Cameroon, International Network of Pasteur Institutes, Yaounde, Cameroon.
Mohamadou Njankouo-RipaCentre Pasteur of Cameroon, International Network of Pasteur Institutes, Yaounde, Cameroon.
Angeladine KenneCentre Pasteur of Cameroon, International Network of Pasteur Institutes, Yaounde, Cameroon.
Véronique Penlap BengDépartement de Biochimie, Université de Yaoundé 1, Yaounde, Cameroun.
Astrid VabretVirology Service, Pôle de Biologie, CHU de Caen, Caen, France.
Richard NjouomCentre Pasteur of Cameroon, International Network of Pasteur Institutes, Yaounde, Cameroon.
Centre Pasteur du Cameroun · CMUniversité de Yaoundé I · CMCentre Hospitalier Universitaire de Caen · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere acute respiratory illness (SARI) is recognized as an important cause of morbidity, mortality, and hospitalization among children in developing countries. Little is known, however, in tropical countries like Cameroon about the cause and seasonality of respiratory infections, especially in hospitalized settings.

objectivesOur study investigates the viral etiology and seasonality of SARI in hospitalized children in Yaounde, Cameroon.

methodsProspective clinic surveillance was conducted to identify hospitalized children aged ≤15 years presenting with respiratory symptoms ≤5-day duration. Demographic and clinical data, and respiratory specimens were collected. Nasopharyngeal samples were tested for 17 respiratory viruses using a multiplex polymerase chain reaction. The viral distribution and demographic data were statistically analyzed.

resultsFrom September 2011 through September 2013, 347 children aged ≤15 years were enrolled. At least one virus was identified in each of 65·4% children, of which 29·5% were coinfections; 27·3% were positive for human adenovirus (hAdV), 13·2% for human respiratory syncytial virus (hRSV), 11·5% for rhinovirus/enterovirus (RV/EV), 10·6% for human bocavirus (hBoV), 9·8% for influenza virus (Inf), 6·6% for human parainfluenza virus (hPIV), 5·7% for human coronavirus (hCoV), and 2·3% for human metapneumovirus (hMPV). While hRSV showed seasonal patterns, hAdV and RV/EV were detected throughout the year and no evident temporal patterns were observed for the remaining viruses.

conclusionRespiratory viruses were associated with a high burden of hospitalizations among children in Cameroon. Nevertheless, additional studies evaluating asymptomatic Cameroonian children will be important in understanding the relationship between viral carriage and disease.

Indexed as

Acute DiseaseAdolescentCameroonCarrier StateChildChild, PreschoolCoinfectionCost of IllnessEpidemiological MonitoringFemaleHospitalizationHuman bocavirusHumansInfantMaleMultiplex Polymerase Chain ReactionAfricaCameroonetiologysevere acute respiratory infectionsvirus

Identifiers

PMID27012372
PMCPMC4947949
OpenAlexW2305692534

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.