Evidence map›Paper›PMID 27012243›Full record

Observational studyBMC nephrology2016

KNOW-Ped CKD (KoreaN cohort study for outcomes in patients with pediatric CKD): Design and methods.

Hee Gyung Kang, Hyun Jin Choi, Kyung Hee Han, Seong Heon Kim, Hee Yeon Cho, Min Hyun Cho, Jae Il Shin, Joo Hoon Lee, Joongyub Lee, Kook Hwan Oh and 4 more

Registry-linked trialOpen access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02165878 (KoreaN Cohort Study for Outcome in Pediatric Patients With Chronic Kidney Disease), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02165878 unknown statusnot on this map

KoreaN Cohort Study for Outcome in Pediatric Patients With Chronic Kidney Disease : A 10-year Longitudinal Cohort Study of the Chronic Kidney Disease

TypeobservationalSponsorSeoul National University HospitalRan2011 to 2021Enrolled458ConditionsChronic Kidney Disease(CKD)
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Hee Gyung KangDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, South Korea.ORCID http://orcid.org/0000-0001-8323-5320
Hyun Jin ChoiDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, South Korea.
Kyung Hee HanDepartment of Pediatrics, Jeju University Hospital, Jeju, South Korea.
Seong Heon KimDepartment of Pediatrics, Pusan National University Children's Hospital, Yangsan, South Korea.
Hee Yeon ChoDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Min Hyun ChoDepartment of Pediatrics, Kyungpook National University School of Medicine, Daegu, South Korea.
Jae Il ShinDepartment of Pediatrics, Yonsei University College of Medicine, Severance Children's Hospital, Seoul, South Korea.
Joo Hoon LeeDepartment of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Joongyub LeeDepartment of Preventive Medicine, Seoul National University Hospital, Seoul, South Korea.
Kook Hwan OhDepartment of Internal Medicine, Seoul National University Children's Hospital, Seoul, South Korea.
Young Seo ParkDepartment of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Hae Il CheongDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, South Korea.
Curie AhnDepartment of Internal Medicine, Seoul National University Children's Hospital, Seoul, South Korea. curie@snu.ac.kr.
Il-Soo HaDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, South Korea. ilsooha@snu.ac.kr.
Seoul National University Children's Hospital · KRUlsan College · KRJeju National University Hospital · KRKyungpook National University · KRPusan National University Yangsan Hospital · KRSamsung Medical Center · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe global prevalence of chronic kidney disease (CKD) is increasing. In children, CKD exhibits unique etiologies and can have serious impacts on children's growth and development. Therefore, an aggressive approach to preventing the progression of CKD and its complications is imperative. To improve the understanding and management of Asian pediatric patients with CKD, we designed and launched KNOW-Ped CKD (KoreaN cohort study for Outcome in patients With Pediatric Chronic Kidney Disease), a nationwide, prospective, and observational cohort study of pediatric CKD with funding from the Korean government. METHODS/

designFrom seven major centers, 450 patients <20 years of age with CKD stages I to V are recruited for the comprehensive assessment of clinical findings, structured follow-up, and bio-specimen collection. The primary endpoints include CKD progression, defined as a decline of estimated glomerular filtration rate by 50 %, and a requirement for renal replacement therapy or death. The secondary outcomes include the development of left ventricular hypertrophy or hypertension, impairment of growth, neuropsychological status, behavioral status, kidney growth, and quality of life. DISCUSSION: With this study, we expect to obtain more information on pediatric CKD, which can be translated to better management for the patients.

trial registrationNCT02165878 (ClinicalTrials.gov), submitted on June 11, 2014.

Indexed as

AdolescentAdolescent DevelopmentChildChild DevelopmentChild, PreschoolCohort StudiesDisease ProgressionFemaleGrowth DisordersHumansHypertensionHypertrophy, Left VentricularInfantInfant, NewbornKidney Failure, ChronicMaleAsian childrenChronic kidney diseaseCohort studyDesignPrognostic factor

Identifiers

PMID27012243
PMCPMC4807586
OpenAlexW2303661378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.