Evidence map›Paper›PMID 27012231›Full record

ArticleJournal of mathematical biology2016

A two phase field model for tracking vesicle-vesicle adhesion.

Rui Gu, Xiaoqiang Wang, Max Gunzburger

Abstract read
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In one paragraph

Article in Journal of mathematical biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rui GuDepartment of Scientific Computing, Florida State University, Tallahassee, FL, 32306-4120, USA. rg10e@fsu.edu.
Xiaoqiang WangDepartment of Scientific Computing, Florida State University, Tallahassee, FL, 32306-4120, USA.
Max GunzburgerDepartment of Scientific Computing, Florida State University, Tallahassee, FL, 32306-4120, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A multi-phase-field model for simulating the adhesion between two vesicles is constructed. Two phase field functions are introduced to simulate each of the two vesicles. An energy model is defined which accounts for the elastic bending energy of each vesicle and the contact potential energy between the two vesicles; the vesicle volume and surface area constraints are imposed using a penalty method. Numerical results are provided to verify the efficacy of our model and to provide visual illustrations of the different types of contact. The method can be adjusted to solve endocytosis problems by modifying the bending rigidity coefficients of the two elastic bending energies. The method can also be extended to simulate multi-cell adhesions, one example of which is erythrocyte rouleaux. A comparison with laboratory observations demonstrates the effectiveness of the multi-phase field approach.

Indexed as

Models, BiologicalCell AdhesionEnergy MetabolismTransport VesiclesElastic bending energyEndocytosisEnergetic variational formulationErythrocyte rouleauxFast Fourier transformLipid bilayerPhase-field modelThree-dimensional simulationsVesicle membranes

Identifiers

PMID27012231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.