Evidence map›Paper›PMID 27011879›Full record

ArticleTurkish journal of urology2016

Antimicrobial susceptibilities of Escherichia coli isolates as agents of community-acquired urinary tract infection (2008-2014).

Nisel Yılmaz, Neval Ağuş, Arzu Bayram, Pınar Şamlıoğlu, M Cem Şirin, Yeşer Karaca Derici, Sevgi Yılmaz Hancı

Open access · greenAbstract read
In one paragraph

Article in Turkish journal of urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
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  5. Article
  6. Biofilm Formation byMicroorganisms · 2023
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  13. Article
  14. Antimicrobial Susceptibilities and Laboratory Profiles ofMedical sciences (Basel, Switzerland) · 2020
    Article
  15. Article
  16. Impact of Sequential Passaging on Protein Expression ofInternational journal of microbiology · 2020
    Article
  17. Article
  18. Community-Acquired Urinary Tract Infection byBioMed research international · 2018
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nisel YılmazClinic of Microbiology, İzmir Tepecik Training and Research Hospital, İzmir, Turkey.
Neval AğuşClinic of Microbiology, İzmir Tepecik Training and Research Hospital, İzmir, Turkey.
Arzu BayramClinic of Microbiology, İzmir Tepecik Training and Research Hospital, İzmir, Turkey.
Pınar ŞamlıoğluClinic of Microbiology, İzmir Tepecik Training and Research Hospital, İzmir, Turkey.
M Cem ŞirinClinic of Microbiology, İzmir Tepecik Training and Research Hospital, İzmir, Turkey.
Yeşer Karaca DericiClinic of Microbiology, İzmir Tepecik Training and Research Hospital, İzmir, Turkey.
Sevgi Yılmaz HancıClinic of Microbiology, İzmir Tepecik Training and Research Hospital, İzmir, Turkey.
Izmir Tepecik Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveUrinary tract infections (UTIs) are among the most frequently seen community-acquired infections worldwide. E. coli causes 90% of urinary system infections. To guide the empirical therapy, the resistance pattern of E. coli responsible for community-acquired UTI was evaluated throughout a seven-year period in this study. MATERIAL AND

methodsThe urine cultures of patients with urinary tract infections admitted to outpatient clinics between 1(st) January 2008 and 31(st) December 2014 were analyzed. Presence of ≥10(5) colony-forming units/mL in urine culture media was considered as significant for UTI. Isolated bacteria were identified by standard laboratory techniques or automated system VITEK2 (BioMerieux, France) and BD PhoenixTM 100 (BD, USA), as required. Antibiotic susceptibility testing was performed by Kirby-Bauer disk diffusion method using Clinical Laboratory Standard Institute (CLSI) criteria.

resultsA total of 13281 uropathogens were isolated. Overall E. coli accounted for 8975 (67%) of all isolates. Resistance rates of E. coli to antimicrobial agents was demonstrated to be as follows: ampicillin 66.9%, cefazolin 30.9%, cefuroxime 30.9%, ceftazidime 14.9%, cefotaxime 28%, cefepime 12%, amoxicillin-clavulanic acid 36.9%, trimethoprim-sulfamethoxazole (TMP-SXT) 20%, ciprofloxacin 49.9%, amikacin 0.3%, gentamycin 24%, nitrofurantoin 0.9%, and fosfomycin 4.3%. There was no resistance to imipenem nor meropenem. The frequency of ESBL-producing E. coli strains was 24%.

conclusionIt is concluded that fosfomycin and nitrofurantoin are appropriate empirical therapy for community-acquired UTI empirical therapy, but the fluoroquinolones and the TMP-SXT shall not be used in the emprical treatment of UTI at this stage. In conclusion, as resistance rates show regional differences, it is necessary to regularly examine regional resistance rates to determine the appropriate empiric antibiotic treatment and national antibiotic usage policies must be reorganized according to data obtained from these studies.

Indexed as

Antimicrobial susceptibilitycommunity-acquired urinary tract infectionsEscherichia coli

Identifiers

PMID27011879
PMCPMC4791079
OpenAlexW2418359143

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.