ArticleJournal of sport and health science2013
Human neuromuscular structure and function in old age: A brief review.
Article in Journal of sport and health science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 78 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Reliability of the Elbow Isotonic Contraction Test as an Alternative to the Gait Speed Test in Assessing Sarcopenia Severity
Innovative Hand Rehabilitation System With Synchronized Contralateral Haptic Feedback
Who cites it
78 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Progressive Resistance Training for Concomitant Increases in Muscle Strength and Bone Mineral Density in Older Adults: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Characterizing Submental Neuromuscular Activity of Swallowing Rehabilitation: An Electromyographic Evaluation of Rehabilitative Maneuvers in Healthy Adults.Journal of speech, language, and hearing research : JSLHR · 2026Trial
- Trial
- A novel upper-extremity-based performance test for sarcopenia: reliability and clinical utility of the elbow performance test.Irish journal of medical science · 2026Trial
- Effects of 12-week whole-body vibration training versus resistance training in older people with sarcopenia.Scientific reports · 2025Trial
- Age-related changes in mobility assessments correlate with repetitive goal-directed arm-movement performance.BMC geriatrics · 2023Trial
- Adaptations in mechanical muscle function, muscle morphology, and aerobic power to high-intensity endurance training combined with either traditional or power strength training in older adults: a randomized clinical trial.European journal of applied physiology · 2020Trial
- Sex differences in the effect of fish-oil supplementation on the adaptive response to resistance exercise training in older people: a randomized controlled trial.The American journal of clinical nutrition · 2017Trial
- Inhibiting Glutaminase Reverses Senescence-Associated Mitochondrial Dysfunction and Skeletal Muscle Decline.Aging cell · 2026Article
- Passive thigh heating increases peak torque but does not attenuate declines in force production during repeated isokinetic knee extensor exercise in older adults.Physiological reports · 2026Article
- From Athletic Performance to Functional Ageing: Shared Genetic Architecture, Redox-Inflammatory Pathways and Functional Reserve Across the Life Course-A Narrative Review.Biomedicines · 2026Review
- Muscle fibre denervation in ageing.Clinical science (London, England : 1979) · 2026Review
- The contribution of age and sex hormones to female neuromuscular function across the adult lifespan.The Journal of physiology · 2026Article
- Exploring neuronal mechanisms of osteosarcopenia in older adults.The Journal of physiology · 2026Review
- Association of preoperative ankle reflex with skeletal muscle loss and poorer physical performance 6 months after gastrectomy in elderly patients with gastric cancer.Frontiers in medicine · 2026Article
- Time to Reset: The Interplay Between Circadian Rhythms and Redox Homeostasis in Skeletal Muscle Ageing and Systemic Health.Antioxidants (Basel, Switzerland) · 2025Review
- Age-related differences in muscular coordination while performing elbow flexion and extension movements at different velocities.Scientific reports · 2025Article
- Klotho Deficiency Promotes Skeletal Muscle Weakness and Is Associated with Impaired Motor Unit Connectivity.International journal of molecular sciences · 2025Article
- Klotho deficiency promotes skeletal muscle weakness and is associated with impaired motor unit connectivity.bioRxiv : the preprint server for biology · 2025Article
- Development and testing of range of motion driven motor unit recruitment device for knee rehabilitation: A randomized controlled trial.MethodsX · 2025Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural adult aging is associated with many functional impairments of the human neuromuscular system. One of the more observable alterations is the loss of contractile muscle mass, termed sarcopenia. The loss of muscle mass occurs primarily due to a progressive loss of viable motor units, and accompanying atrophy of remaining muscle fibers. Not only does the loss of muscle mass contribute to impaired function in old age, but alterations in fiber type and myosin heavy chain isoform expression also contribute to weaker, slower, and less powerful contracting muscles. This review will focus on motor unit loss associated with natural adult aging, age-related fatigability, and the age-related differences in strength across contractile muscle actions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.