ArticleEuropean journal of dentistry
Patient-centered evaluation of microsurgical management of gingival recession using coronally advanced flap with platelet-rich fibrin or amnion membrane: A comparative analysis.
Article in European journal of dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 7 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- Autologous platelet concentrates in root coverage procedures.Periodontology 2000 · 2025Pooled it
- Microsurgery in periodontics and oral implantology: a systematic review of current clinical applications and outcomes.Evidence-based dentistry · 2024Pooled it
- Efficacy of amniotic membrane with coronally advanced flap in the treatment of gingival recession: an updated systematic review and meta-analysis.BMC oral health · 2024Pooled it
- Efficacy of microsurgery and comparison to macrosurgery for gingival recession treatment: a systematic review with meta-analysis.Clinical oral investigations · 2021Pooled it
- Effectiveness of connective tissue graft substitutes for the treatment of gingival recessions compared with coronally advanced flap: a network meta-analysis.Clinical oral investigations · 2020Pooled it
- Use of platelet-rich fibrin for the treatment of gingival recessions: a systematic review and meta-analysis.Clinical oral investigations · 2020Pooled it
- Use of platelet-rich fibrin in regenerative dentistry: a systematic review.Clinical oral investigations · 2017Pooled it
- A comparative study of the effects of advanced platelet-rich fibrin and resorbable collagen membrane in the treatment of gingival recession: a split-mouth, randomized clinical trial.Head & face medicine · 2024Trial
- Evaluation of low-level laser therapy and platelet-rich fibrin on donor site healing after vascularized interpositional periosteal connective tissue flap: a randomized clinical study.Lasers in medical science · 2023Trial
- Coronally advanced flap with platelet-rich fibrin or amniotic membrane for the treatment of gingival recession: a systematic review and meta-analysis with trial sequential analysis.Evidence-based dentistry · 2026Article
- Management of isolated gingival recession defects using platelet rich fibrin and amnio-chorion membrane in coronally advanced flap: an in-vivo study.The Saudi dental journal · 2026Article
- Surgical approaches for the treatment of different cases of gingival recessions: a case report.Journal of surgical case reports · 2026Article
- Article
- Optimizing Esthetics in Maxillary Anterior Periradicular Surgery: A Case Report on Vestibular Incision.Case reports in dentistry · 2026Article
- Amniotic Allograft with Coronally Advanced Flap for Treatment of Gingival Recession: A Randomized, Controlled Clinical Trial.Frontiers in dentistry · 2025Article
- Efficacy of autologous platelet concentrates for root coverage of Miller's Class I and II gingival recession defects: A systematic review and meta-analysis.Dental research journal · 2024Review
- Comparison of Histological, Clinical, and Radiographic Outcomes of Postextraction Ridge Preservation by Allogenic Bone Grafting With and Without Injectable Platelet-Rich Fibrin: A Double-Blinded Randomized Controlled Clinical Trial.International journal of dentistry · 2024Article
- Amniotic membrane versus platelet-rich fibrin in treatment of gingival recession- a randomized control trial.The Saudi dental journal · 2024Article
- Quantitative Association of Platelet-Rich Fibrin (PRF) and Hyperacute Serum (HAS) with Glycemic Control (HbA1c) in Chronic Periodontitis Patients: An Ex vivo Study.Journal of pharmacy & bioallied sciences · 2023Article
- Clinical Efficacy of Platelet Derivatives in Periodontal Tissue Regeneration: An Umbrella Review.International journal of dentistry · 2023Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the efficacy of coronally advanced flap (CAF) procedure under microsurgical approach for the management of Miller's Class I and II gingival recession defects with the use of either platelet-rich fibrin (PRF) or amnion membrane (AM) in comparison to CAF alone. MATERIALS AND
methodsA total of 45 sites with Miller's Class I or II gingival recession defect were randomly distributed for: Experimental Group I (CAF with PRF) sites (n = 15) which were treated with the microsurgical approach using CAF along with PRF; experimental Group II (CAF with AM) sites (n = 15) were treated with the microsurgical approach using CAF along with AM; control Group III (CAF alone) sites (n = 15) were treated with the microsurgical approach using CAF alone. Vertical gingival recession (VGR), horizontal gingival recession (HGR), gingival thickness (GT) (using transgingival probing [TGP] and ultrasonography [USG]) and patients' response and acceptance were documented at baseline, 3 months and 6 months after surgical interventions.
resultsCAF alone and in combination with PRF or AM, were effective techniques for root coverage with average VGR values of 1.47 ± 0.92 mm (56%), 0.67 ± 1.23 mm (36%) and 0.60 ± 1.06 mm (33%) in Group I (CAF with PRF), Group II (CAF with AM), and Group III (CAF alone), respectively. Complete coverage (100%) was obtained in 33.3% sites of Group I (CAF with PRF), 26.6% sites of Group II (CAF with AM) and 13.3% in Group III (CAF alone). Patients' response and acceptance for surgical treatment modality in terms of patient esthetic score and decrease in hypersensitivity score was highest for Group I (CAF with PRF), whereas patient comfort score was highest for Group II (CAF with AM). At 6 months follow-up, significant increase in GT measurements (using TGP and USG) in Group I (CAF with PRF), whereas, nonsignificant increase for Group II (CAF with AM) and no change or decrease for Group III (CAF alone) as compared to baseline was observed.
conclusionThe present study observed enhancement in root coverage when PRF or AM are used in conjunction with CAF as compared to CAF alone. These results are based on 6-month follow-up. Therefore, the long-term evaluation may be necessary to appreciate the clinical effect of autologous PRF and AM.
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