ArticleAnnals of pediatric cardiology
Clarifying the anatomy of the fifth arch artery.
Article in Annals of pediatric cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Rare Variant of a Rare Anomaly: Stenotic Persistent Right-Sided Fifth Aortic Arch with Fourth Arch Interruption.CASE (Philadelphia, Pa.) · 2026Article
- Case Report: Persistent fifth aortic arch with coarctation and fourth aortic arch interruption causing infant heart failure - the prenatal and postnatal echocardiographic course.Frontiers in medicine · 2026Article
- Persistent fifth aortic arch complicated by Williams-Beuren syndrome: a case description.Quantitative imaging in medicine and surgery · 2025Article
- Two critical events in the development of the vascular system: pruning and remodeling.Clinical and experimental medicine · 2025Review
- Case Report: A case of persistent fifth aortic arch associated with stenosis and interrupted aortic arch.Frontiers in pediatrics · 2025Article
- Echocardiography of persistent fifth aortic arch confirmed by computed tomography angiography or surgery in children: a case series.BMC cardiovascular disorders · 2024Article
- Cinematic Rendering of Persistent Fifth Aortic Arch with Aortic Coarctation and Bicuspid Aortic Valve.The Indian journal of radiology & imaging · 2024Article
- Persistent fifth aortic arch: a comprehensive literature review.Frontiers in pediatrics · 2023Review
- Entrance and origin of the extracranial vertebral artery found on computed tomography angiography.Scientific reports · 2022Article
- Surgical repair of persistent fifth aortic arch coarctation and interrupted fourth aortic arch without cardiopulmonary bypass: a case report.Translational pediatrics · 2022Article
- Persistent fifth aortic arch associated with aortic coarctation: a case of surgical correction without artificial material.Journal of cardiothoracic surgery · 2021Article
- Persistent fifth aortic arch: a single-center experience, case series.Translational pediatrics · 2021Article
- Embryological development of the human cranio-facial arterial system: a pictorial review.Surgical and radiologic anatomy : SRA · 2021Review
- Left Pulmonary Artery from the Ascending Aorta: A Case Report and Review of Published Cases.Journal of cardiovascular development and disease · 2020Article
- Anomalous Left-to-Right Shunting Vessel between the Ascending Aorta and Right Pulmonary Artery and Concurrent Left Peripheral Pulmonary Artery Stenosis in a Dog.CASE (Philadelphia, Pa.) · 2020Article
- A case report: stent implantation to treat coarctation of persistent 5th aortic arch associated with interrupted 4th aortic arch.European heart journal. Case reports · 2019Article
- The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic arch.Disease models & mechanisms · 2019Article
- Congenital anomalies of the aortic arch.Cardiovascular diagnosis and therapy · 2018Review
- How Should We Diagnose Persistence of the Artery of the Fifth Pharyngeal Arch?Pediatric cardiology · 2017Article
- Isolated persistence of the fifth aortic arch in an infant presenting with congestive heart failure.Annals of pediatric cardiologyArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The artery allegedly forming in the fifth pharyngeal arch has increasingly been implicated as responsible for various vascular malformations in patients with congenitally malformed hearts. Observations from studies on developing embryos, however, have failed to provide support to substantiate several of these inferences such that the very existence of the fifth arch artery remains debatable. To the best of our knowledge, in only a solitary human embryo has a vascular channel been found that truly resembled the artery of the fifth arch. Despite the meager evidence to support its existence, the fifth arch artery has been invoked to explain the morphogenesis of double-barreled aorta, some unusual forms of aortopulmonary communications, and abnormalities of the brachiocephalic arteries. In most of these instances, the interpretations have proved fallible when examined in the light of existing knowledge of cardiac development. In our opinion, there are more plausible alternative explanations for the majority of these descriptions. Double-barreled aorta is more likely to result from retention of the recently identified dorsal collateral channels while abnormalities of brachiocephalic arteries are better explained on the basis of extensive remodeling of aortic arches during fetal development. Some examples of aortopulmonary communications, nonetheless, may well represent persistence of the developing artery of the fifth pharyngeal arch. We here present one such case - a patient with tetralogy of Fallot and pulmonary atresia, in whom the fifth arch artery provided a necessary communication between the ascending aorta and the pulmonary arteries. In this light, we discuss the features we consider to be essential before attaching the tag of "fifth arch artery" to a candidate vascular channel.
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