ArticleIndian journal of psychological medicine
Neurocognitive Functioning in Schizophrenia, their Unaffected Siblings and Healthy Controls: A Comparison.
Article in Indian journal of psychological medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Can artificial intelligence be the future solution to the enormous challenges and suffering caused by Schizophrenia?Schizophrenia (Heidelberg, Germany) · 2025Review
- Slow Binocular Rivalry as a Potential Endophenotype of Schizophrenia.Frontiers in neuroscience · 2018Article
- Comment on: Neurocognitive Functioning in Schizophrenia, Their Unaffected Siblings and Healthy Controls: A Comparison.Indian journal of psychological medicineArticle
- Neurocognitive Profile in Indian Individuals Genetically at Risk of Schizophrenia.Indian journal of psychological medicineArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimNeurocognitive functions are considered to be reliable endophenotypes for schizophrenia. This study aimed to study the neurocognitive functioning of unaffected siblings of patients with schizophrenia and compare the same with a group of patients with schizophrenia and a group of healthy controls. MATERIALS AND
methodsThree study groups, that is, unaffected siblings of patients with schizophrenia, patients of schizophrenia and healthy controls, each group comprising of 20 participants were evaluated on Wisconsin Card Sorting Test, Brief Visuospatial Memory Test-Revised, Hopkins Verbal Learning Test-Revised, Wechsler Adult Intelligence Scale and Digit Symbol Test.
resultsCompared to healthy controls, unaffected siblings of patients with schizophrenia performed poorly on the tests of short-term verbal learning and memory, but no significant differences were seen between the two groups for executive functions, visual learning and psychomotor speed, concentration and graphomotor abilities. However, when compared with patients with schizophrenia, unaffected siblings performed poorly on the tests of executive functions, visual memory, verbal memory, psychomotor speed, concentration and graphomotor abilities.
conclusionCognitive markers like verbal memory deficits can distinguish unaffected siblings of schizophrenia from healthy controls and serve as an endophenotype for schizophrenia.
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