Evidence map›Paper›PMID 27011374›Full record

ArticleEuropean radiology2017

Extracranial Venous abnormalities: A true pathological finding in patients with multiple sclerosis or an anatomical variant?

Carlos Torres, Matthew Hogan, Satya Patro, Santanu Chakraborty, Thanh Nguyen, Rebecca Thornhill, Mark Freedman, Miguel Bussiere, Hamid Dabirzadeh, Betty Anne Schwarz and 4 more

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Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Carlos TorresDepartment of Radiology, University of Ottawa, Ottawa, ON, K1Y 4E9, Canada. catorres@toh.on.ca.
Matthew HoganOttawa Hospital Research Institute OHRI, Ottawa, ON, Canada.
Satya PatroDepartment of Radiology, University of Ottawa, Ottawa, ON, K1Y 4E9, Canada.
Santanu ChakrabortyDepartment of Radiology, University of Ottawa, Ottawa, ON, K1Y 4E9, Canada.
Thanh NguyenDepartment of Radiology, University of Ottawa, Ottawa, ON, K1Y 4E9, Canada.
Rebecca ThornhillDepartment of Radiology, University of Ottawa, Ottawa, ON, K1Y 4E9, Canada.
Mark FreedmanOttawa Hospital Research Institute OHRI, Ottawa, ON, Canada.
Miguel BussiereDepartment of Medicine, Division of Neurology, University of Alberta, Edmonton, Canada.
Hamid DabirzadehDepartment of Radiology, University of Saskatchewan, Neuroradiologist, Saskatoon, Canada.
Betty Anne SchwarzDepartment of Medical Imaging, The Ottawa Hospital, 1053 Carling Ave, Ottawa, ON, Canada.
Stefanie BelangerDepartment of Medical Imaging, The Ottawa Hospital, 1053 Carling Ave, Ottawa, ON, Canada.
Lysa Legault-KingstoneDepartment of Medical Imaging, The Ottawa Hospital, 1053 Carling Ave, Ottawa, ON, Canada.
Mark SchweitzerDepartment of Radiology, Stony Brook School of Medicine, Stony Brook, NY, USA.
Cheemun LumDepartment of Radiology, University of Ottawa, Ottawa, ON, K1Y 4E9, Canada.
Ottawa Hospital · CAOttawa Hospital Research InstituteUniversity of Ottawa · CAStony Brook School · USUniversity of Alberta · CAUniversity of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the extracranial venous anatomy with contrast-enhanced MR venogram (CE-MRV) in patients without multiple sclerosis (MS), and assess the prevalence of various venous anomalies such as asymmetry and stenosis in this population. MATERIALS AND

methodsWe prospectively recruited 100 patients without MS, aged 18-60 years, referred for contrast-enhanced MRI. They underwent additional CE-MRV from skull base to mediastinum on a 3T scanner. Exclusion criteria included prior neck radiation, neck surgery, neck/mediastinal masses or significant cardiac or pulmonary disease. Two neuroradiologists independently evaluated the studies to document asymmetry and stenosis in the jugular veins and prominence of collateral veins.

resultsAsymmetry of internal jugular veins (IJVs) was found in 75 % of subjects. Both observers found stenosis in the IJVs with fair agreement. Most stenoses were located in the upper IJV segments. Asymmetrical vertebral veins and prominence of extracranial collateral veins, in particular the external jugular veins, was not uncommon.

conclusionIt is common to have stenoses and asymmetry of the IJVs as well as prominence of the collateral veins of the neck in patients without MS. These findings are in contrast to prior reports suggesting collateral venous drainage is rare except in MS patients. KEY POINTS: • The venous anatomy of the neck in patients without MS demonstrates multiple variants • Asymmetry and stenoses of the internal jugular veins are common • Collateral neck veins are not uncommon in patients without MS • These findings do not support the theory of chronic cerebrospinal venous insufficiency • MR venography is a useful imaging modality for assessing venous anatomy.

Indexed as

AdolescentAdultCollateral CirculationConstriction, PathologicFemaleHumansJugular VeinsMagnetic Resonance AngiographyMagnetic Resonance ImagingMaleMediastinumMiddle AgedMultiple SclerosisNeckObserver VariationPrevalenceContrast-enhanced MR venographyInternal jugular veinsNeckStenosisVenous anatomy

Identifiers

PMID27011374
OpenAlexW2311684327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.