Evidence map›Paper›PMID 27011180›Full record

ReviewInternational journal of molecular sciences2016

Molecular Insight into Gut Microbiota and Rheumatoid Arthritis.

Xiaohao Wu, Bing He, Jin Liu, Hui Feng, Yinghui Ma, Defang Li, Baosheng Guo, Chao Liang, Lei Dang, Luyao Wang and 6 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. D-serine metabolism enhancesCurrent research in microbial sciences · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Peptide BG From Bitter Gourd (Mediators of inflammation · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
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  16. Article
  17. Article
  18. Article
  19. Article
  20. Therapeutic Advances in Diabetes, Autoimmune, and Neurological Diseases.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xiaohao WuInstitute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. wxho0606@163.com.
Bing HeInstitute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. hebinghb@gmail.com.
Jin LiuInstitute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. liujin_hkbu@163.com.
Hui FengGuanghua Integrative Hospital, Shanghai 200000, China. 13816671472@163.com.
Yinghui MaGuanghua Integrative Hospital, Shanghai 200000, China. mayinghui021@126.com.
Defang LiInstitute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. lidefang@163.com.
Baosheng GuoInstitute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. borisguo@hkbu.edu.hk.
Chao LiangInstitute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. liangchao512@163.com.
Lei DangInstitute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. danglei_hkbu@163.com.
Luyao WangInstitute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. luyaoben@126.com.
Jing TianInstitute of Arthritis Research, Shanghai Academy of Chinese Medical Sciences, Shanghai 200000, China. 14441098@life.hkbu.edu.hk.
Hailong ZhuInstitute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. hlzhu@hkbu.edu.hk.
Lianbo XiaoGuanghua Integrative Hospital, Shanghai 200000, China. 13701888178@163.com.
Cheng LuInstitute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. lv_cheng0816@163.com.
Aiping LuInstitute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. aipinglu@hkbu.edu.hk.
Ge ZhangInstitute for Advancing Translational Medicine in Bone & Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China. zhangge@hkbu.edu.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a systemic, inflammatory, and autoimmune disorder. Gut microbiota play an important role in the etiology of RA. With the considerable progress made in next-generation sequencing techniques, the identified gut microbiota difference between RA patients and healthy individuals provides an updated overview of the association between gut microbiota and RA. We reviewed the reported correlation and underlying molecular mechanisms among gut microbiota, the immune system, and RA. It has become known that gut microbiota contribute to the pathogenesis of RA via multiple molecular mechanisms. The progressive understanding of the dynamic interaction between gut microbiota and their host will help in establishing a highly individualized management for each RA patient, and achieve a better efficacy in clinical practice, or even discovering new drugs for RA.

Indexed as

MicrobiotaAnimalsArthritis, RheumatoidHumansIntestinesgut microbiotamolecular mechanismrheumatoid arthritis

Identifiers

PMID27011180
PMCPMC4813281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.