Evidence map›Paper›PMID 27010532›Full record

ArticlePloS one2016

Geriatric Nutritional Risk Index (GNRI) Independently Predicts Amputation Inchronic Criticallimb Ischemia (CLI).

Han Luo, Hongliu Yang, Bin Huang, Ding Yuan, Jingqiang Zhu, Jichun Zhao

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 44 citations in OpenAlex.

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  15. Impact of malnutrition and frailty on mortality and major amputation in patients with CLTI.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Han LuoDepartment of Vascular Surgery, West China Hospital, Sichuan University, Chengdu, China.
Hongliu YangDepartment of Nephrology, Biostatistics Center, West China Hospital, Sichuan University, Chengdu, China.
Bin HuangDepartment of Nephrology, Biostatistics Center, West China Hospital, Sichuan University, Chengdu, China.
Ding YuanDepartment of Vascular Surgery, West China Hospital, Sichuan University, Chengdu, China.
Jingqiang ZhuDepartment of Thyroid & Parathyroid Surgery, West China Hospital, Sichuan University, Chengdu, China.
Jichun ZhaoDepartment of Vascular Surgery, West China Hospital, Sichuan University, Chengdu, China.
Sichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGeneral malnutrition usually occurs in critical limb ischemia (CLI) patients because of shortness of appetite and sleeplessness leaded by chronic pain. And amputation frequently is end-point of CLI patients. So the aim of this study was to assess the predictive ability of Geriatric nutritional risk index (GNRI) for predicting amputation in patients with CLI.

methodsA retrospective study was designed. Demographics, history, comorbidity, and risk factors for peripheral vascular disease of admitted patients, and laboratory study were documented. Patients' height, weight and BMI were recorded. Amputation was identified as end-point during follow-up. Patients' amputation-free survival (AFS) was recorded.

result172 patients were identified, with mean age 71.98±3.12. Geriatric nutritional risk index (GNRI) = 90 was taken as cutoff value of high risk of amputation for CLI patients via using receiver operating characteristic (ROC) curve. Span of follow-up was 12-48 months. During follow-up, 60 patients (36.04%) received amputation surgery. And analyzed by Cox proportional hazards model, it is found that GNRI was the independent predictive factor for amputation in long term.

conclusionThis study revealed that GNRI was a reliable and effective predictive marker for AFS. GNRI could identify patients with high risk for amputation in early time.

Indexed as

Amputation, SurgicalGeriatric AssessmentNutritional StatusAgedExtremitiesHumansMiddle AgedRetrospective StudiesRisk Assessment

Identifiers

PMID27010532
PMCPMC4806865
OpenAlexW2310729286

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.