Evidence map›Paper›PMID 27010253›Full record

SynthesisScandinavian journal of primary health care2016

Atopic dermatitis, asthma and allergic rhinitis in general practice and the open population: a systematic review.

D H J Pols, J B Wartna, H Moed, E I van Alphen, A M Bohnen, P J E Bindels

Open access · goldAbstract readComparative StudySystematic Review
In one paragraph

Synthesis in Scandinavian journal of primary health care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 5 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 5 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Pooled it
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  5. Allergies and Childhood Acute Lymphoblastic Leukemia: A Case-Control Study and Meta-analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018
    Pooled it
  6. Trial
  7. Article
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  10. Incidence and Prevalence of Childhood Atopic Diseases in Dutch Primary Care.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

D H J Polsa Department of General Practice, Erasmus MC , University Medical Center Rotterdam , The Netherlands.
J B Wartnaa Department of General Practice, Erasmus MC , University Medical Center Rotterdam , The Netherlands.
H Moeda Department of General Practice, Erasmus MC , University Medical Center Rotterdam , The Netherlands.
E I van Alphena Department of General Practice, Erasmus MC , University Medical Center Rotterdam , The Netherlands.
A M Bohnena Department of General Practice, Erasmus MC , University Medical Center Rotterdam , The Netherlands.
P J E Bindelsa Department of General Practice, Erasmus MC , University Medical Center Rotterdam , The Netherlands.
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine whether significant differences exist between the self-reported prevalence of atopic disorders in the open population compared with physician diagnosed prevalence of atopic disorders in general practice.

methodsMedline (OvidSP), PubMed Publisher, EMBASE, Google Scholar and the Cochrane Controlled Clinical Trials Register databases were systematically reviewed for articles providing data on the prevalence of asthma, allergic rhinitis and eczema in a GP setting. Studies were only included when they had a cross-sectional or cohort design and included more than 100 children (aged 0-18 years) in a general practice setting. All ISAAC studies (i.e. the open population) that geographically matched a study selected from the first search, were also included. A quality assessment was conducted. The primary outcome measures were prevalence of eczema, asthma and allergic rhinitis in children aged 0-18 years.

resultsThe overall quality of the included studies was good. The annual and lifetime prevalences of the atopic disorders varied greatly in both general practice and the open population. On average, the prevalence of atopic disorders was higher in the open population.

conclusionThere are significant differences between the self-reported prevalence of atopic disorders in the open population compared with physician diagnosed prevalence of atopic disorders in general practice. Data obtained in the open population cannot simply be extrapolated to the general practice setting. This should be taken into account when considering a research topic or requirements for policy development. GPs should be aware of the possible misclassification of allergic disorders in their practice. Key Points Epidemiological data on atopic disorders in children can be obtained from various sources, each having its own advantages and limitations. On average, the prevalence of atopic disorders is higher in the open population. GPs should take into account the possible misclassification of atopic disorders in their practice population. Policymakers should be aware that data obtained in the open population cannot simply be extrapolated to the general practice setting.

Indexed as

Dermatitis, AtopicDiagnostic ErrorsFemaleGeneral PracticeHumansMaleNetherlandsPrevalenceRhinitis, AllergicSelf ReportUnited KingdomAllergic rhinitisasthmaatopic eczemaepidemiologygeneral practiceprimary careThe Netherlands

Identifiers

PMID27010253
PMCPMC4977936
OpenAlexW2305603411

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.