ReviewSocial psychiatry and psychiatric epidemiology2016
The Great Smoky Mountains Study: developmental epidemiology in the southeastern United States.
Review in Social psychiatry and psychiatric epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Does physical activity really improve anxiety and depression in overweight or obese children and adolescents? A systematic review and meta-analysis.BMC psychiatry · 2026Pooled it
- Diagnostic variability of mental disorders in adolescence: A longitudinal study across transition boundary age.JCPP advances · 2026Article
- Incidence, prevalence, and global burden of attention-deficit/hyperactivity disorder from 1990 to 2021 across 204 countries in individuals under age 20: data, with critical appraisal, from the 2021 Global Burden of Disease study.Molecular psychiatry · 2026Article
- Methylome-wide association study in blood suggests cell type-specific relationships between DNA methylation and lifetime anxiety.Nature communications · 2026Article
- Is There Any Level of Stress Exposure That Is Beneficial?Journal of the American Academy of Child and Adolescent Psychiatry · 2026Article
- Mental health of children in high-altitude regions: a bibliometric study and visualization analysis from 1979 to 2024.Annals of general psychiatry · 2025Article
- Mental health of children and young people in the WHO Europe region.The Lancet regional health. Europe · 2025Review
- Childhood allostatic load predicts cardiometabolic health in adulthood.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- State-Level Variation in Racial-Ethnic Disparities in Access to Children's Mental Health Care.Psychiatric services (Washington, D.C.) · 2025Article
- Somatization and Body Composition: Findings from a Cross-Sectional Study on Non-Clinical Young Adults.Healthcare (Basel, Switzerland) · 2025Article
- The biological embedding of social adversity: How adolescent housing insecurity impacts inflammation over time.Brain, behavior, and immunity · 2024Article
- Family cash transfers in childhood and birthing persons and birth outcomes later in life.SSM - population health · 2024Article
- Associations Between Configurations of Childhood Adversity and Adult Mental Health Disorder Outcomes.Society and mental health · 2024Article
- Endocrine Health and Health Care Disparities in the Pediatric and Sexual and Gender Minority Populations: An Endocrine Society Scientific Statement.The Journal of clinical endocrinology and metabolism · 2023Article
- Mental Health and Physical Activity of Female Higher Education Students during the COVID-19 Pandemic: A Comparative Cross-Sectional Study from Lithuania.International journal of environmental research and public health · 2022Article
- Early-childhood temperament moderates the prospective associations of coping with adolescent internalizing and externalizing symptoms.Frontiers in psychology · 2022Article
- Psychometric Properties of The Clinician Affective Reactivity Index for Assessment of Irritability in a Clinical Sample of Turkish Children and Adolescents.Scandinavian journal of child and adolescent psychiatry and psychology · 2022Article
- Early life trauma - review of clinical and neurobiological studies.Postepy psychiatrii neurologii · 2021Review
- Cohort profile: The Youth and Mental Health Study (YAMHS) - a longitudinal study of the period from adolescence to adulthood.PloS one · 2021Article
- Using the tools of genetic epidemiology to understand sex differences in neuropsychiatric disorders.Genes, brain, and behavior · 2020Review
Corrections and comments
- Commented on by
Authors and funding
3 authors.
Funding
Abstract
aimsTo describe the Great Smoky Mountains Study (GSMS).
methodsGSMS is a longitudinal study of child psychiatric disorders that began in 1992 to look at need for mental health services in a rural area of the USA. Over 20 years it has expanded its range to include developmental epidemiology more generally, not only the development of psychiatric and substance abuse problems but also their correlates and predictors: family and environmental risk, physical development including puberty, stress and stress-related hormones, trauma, the impact of poverty, genetic markers, and epigenetics. Now that participants are in their 30s the focus has shifted to adult outcomes of childhood psychopathology and risk, and early physical, cognitive, and psychological markers of aging.
resultsThis paper describes the results from over 11,000 interviews, examples of the study's contributions to science and policy, and plans for the future.
conclusionsLongitudinal studies can provide insights that aid in policy planning.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.