Evidence map›Paper›PMID 27010196›Full record

ArticlePloS one2016

Saccadic Eye Movements in Anorexia Nervosa.

Andrea Phillipou, Susan Lee Rossell, Caroline Gurvich, Matthew Edward Hughes, David Jonathan Castle, Richard Grant Nibbs, Larry Allen Abel

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Andrea PhillipouDepartment of Optometry & Vision Sciences, The University of Melbourne, Melbourne, Victoria, Australia.
Susan Lee RossellBrain and Psychological Sciences Research Centre, Swinburne University of Technology, Hawthorne, Victoria, Australia.
Caroline GurvichMonash Alfred Psychiatry Research Centre, Monash University, Clayton, Victoria, Australia.
Matthew Edward HughesBrain and Psychological Sciences Research Centre, Swinburne University of Technology, Hawthorne, Victoria, Australia.
David Jonathan CastleDepartment of Psychiatry, St Vincent's Hospital, Fitzroy, Victoria, Australia.
Richard Grant NibbsBrain and Psychological Sciences Research Centre, Swinburne University of Technology, Hawthorne, Victoria, Australia.
Larry Allen AbelDepartment of Optometry & Vision Sciences, The University of Melbourne, Melbourne, Victoria, Australia.
Swinburne University of Technology · AUAustralian College of Optometry · AUMonash Alfred Psychiatry Research centre · AUMonash University · AUSt Vincent's Hospital · AUUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnorexia Nervosa (AN) has a mortality rate among the highest of any mental illness, though the factors involved in the condition remain unclear. Recently, the potential neurobiological underpinnings of the condition have become of increasing interest. Saccadic eye movement tasks have proven useful in our understanding of the neurobiology of some other psychiatric illnesses as they utilise known brain regions, but to date have not been examined in AN. The aim of this study was to investigate whether individuals with AN differ from healthy individuals in performance on a range of saccadic eye movements tasks.

methods24 females with AN and 25 healthy individuals matched for age, gender and premorbid intelligence participated in the study. Participants were required to undergo memory-guided and self-paced saccade tasks, and an interleaved prosaccade/antisaccade/no-go saccade task while undergoing functional magnetic resonance imaging (fMRI).

resultsAN participants were found to make prosaccades of significantly shorter latency than healthy controls. AN participants also made an increased number of inhibitory errors on the memory-guided saccade task. Groups did not significantly differ in antisaccade, no-go saccade or self-paced saccade performance, or fMRI findings. DISCUSSION: The results suggest a potential role of GABA in the superior colliculus in the psychopathology of AN.

Indexed as

SaccadesAdolescentAdultAnorexia NervosaCase-Control StudiesFemaleHumansMagnetic Resonance ImagingYoung Adult

Identifiers

PMID27010196
PMCPMC4806909
OpenAlexW2309096490

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.