Evidence map›Paper›PMID 27009602›Full record

ArticleThe Journal of infectious diseases2016

Incident Detection of High-Risk Human Papillomavirus Infections in a Cohort of High-Risk Women Aged 25-65 Years.

Rachel L Winer, James P Hughes, Qinghua Feng, Joshua E Stern, Long Fu Xi, Laura A Koutsky

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

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  13. Prevalence of HPV and associated factors in a population of women living in southern Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
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  18. International journal of biological sciences · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rachel L WinerDepartment of Epidemiology.
James P HughesDepartment of Biostatistics.
Qinghua FengFIDALAB, Seattle, Washington.
Joshua E SternDepartment of Global Health.
Long Fu XiDepartment of Epidemiology Department of Pathology, University of Washington.
Laura A KoutskyDepartment of Epidemiology.
University of Washington · US

Funding

University of Washington STI-TM Cooperative Research CtrU19AI031448 · NIAID · UNIVERSITY OF WASHINGTON · PI HOLMES, KING K. · 1995 to 2010
$15.2M
HPV Infections in Older WomenK01AI079270 · NIAID · UNIVERSITY OF WASHINGTON · PI WINER, RACHEL L. · 2008 to 2011
$581k
NIAID NIH HHS K01 AI079270NIAID NIH HHS U19 AI031448
6 · The paper itself

Abstract

backgroundThe risk of incident high-risk human papillomavirus (HR-HPV) infection associated with recent sexual behaviors is undefined in mid-adult women (defined as women aged 25-65 years).

methodsTriannually, 420 female online daters aged 25-65 years submitted vaginal specimens for HPV testing and completed health and sexual behavior questionnaires. The cumulative incidence of and risk factors for incident HR-HPV detection were estimated by Kaplan-Meier and Cox proportional hazards methods.

resultsThe 12-month cumulative incidence of HR-HPV detection was 25.4% (95% confidence interval [CI], 21.3%-30.1%). Current hormonal contraceptive use was positively associated with incident HR-HPV detection. Lifetime number of male sex partners was also positively associated but only among women not recently sexually active with male partners. In analysis that adjusted for hormonal contraceptive use and marital status, women reporting multiple male partners or male partners who were new, casual, or had ≥1 concurrent partnership had a hazard of incident HR-HPV detection that was 2.81 times (95% CI, 1.38-5.69 times) that for women who reported no male sex partners in the past 6 months. Thus, among women with multiple male partners or male partners who were new, casual, or had ≥1 concurrent partnership, approximately 64% of incident HR-HPV infections were attributable to one of those partners.

conclusionsAmong high-risk mid-adult women with recent new male partners, multiple male partners, or male partners who were casual or had ≥1 concurrent partnership, about two thirds of incident HR-HPV detections are likely new acquisitions, whereas about one third of cases are likely redetections of prior infections.

Indexed as

GenotypeAdultAgedFemaleHumansIncidenceLongitudinal StudiesMaleMiddle AgedPapillomaviridaePapillomavirus InfectionsRisk FactorsSexual BehaviorSurveys and QuestionnairesVaginaHPVhuman papillomavirusincidencemid-adultrisk factorswomen

Identifiers

PMID27009602
PMCPMC4978366
OpenAlexW2304784406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.