ArticleHypertension research : official journal of the Japanese Society of Hypertension2016
Differences in the association between high blood pressure and cognitive functioning among the general Japanese population aged 70 and 80 years: The SONIC study.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Left ventricular hypertrophy in association with cognitive impairment: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Pooled it
- Impact of long-term systolic blood pressure on cognitive disorder risk: Across different age groups and antihypertensive medication timing.Journal of Alzheimer's disease : JAD · 2026Observational
- Multidimensional insights about healthy aging from the cohort study for community-dwelling older adults: The SONIC study.Geriatrics & gerontology international · 2025Review
- Factors associated with weight loss by age among community-dwelling older people.BMC geriatrics · 2023Article
- The factors associated with cognitive function among community-dwelling older adults in Taiwan.BMC geriatrics · 2023Observational
- The relationship between blood pressure and cognitive function.International journal of cardiology. Cardiovascular risk and prevention · 2021Article
- Link of neurocognitive deficit to impaired cardiovagal modulation in prehypertensives is comparable to newly diagnosed hypertensives in young Indian population.American journal of neurodegenerative disease · 2021Article
- The association of blood pressure with physical frailty and cognitive function in community-dwelling septuagenarians, octogenarians, and nonagenarians: the SONIC study.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Day-to-day blood pressure variability is associated with lower cognitive performance among the Japanese community-dwelling oldest-old population: the SONIC study.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Relative validity of brief-type self-administered diet history questionnaire among very old Japanese aged 80 years or older.Public health nutrition · 2019Article
- AAging · 2018Article
- Association between dietary patterns and cognitive function among 70-year-old Japanese elderly: a cross-sectional analysis of the SONIC study.Nutrition journal · 2017Article
- Longitudinal association of hypertension and diabetes mellitus with cognitive functioning in a general 70-year-old population: the SONIC study.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
- Reply to 'Differences in the association between high blood pressure and cognitive functioning among the general Japanese population aged 70 and 80 years'.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
- Differences in the association between high blood pressure and cognitive functioning among the general Japanese population aged 70 to 80 years old: methodological issues to avoid misinterpretation.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
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27 authors.
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Abstract
High blood pressure in middle age (up to 64 years) has been proposed as a predictive indicator of dementia. However, the association between hypertension and the cognitive functioning is controversial in older age groups. The aim of this study was to investigate this association in 70-80-year-old participants in the Japanese study of Septuagenarians, Octogenarians and Nonagenarians Investigation with Centenarians (SONIC). Participants aged 70 (±1) and 80 (±1) years (n=1000 and 973, respectively) were randomly recruited from the general population in Japan. Cognitive functioning was measured by the Montreal Cognitive Assessment. Blood pressure and other medical and social variables were analyzed by multiple regression analyses. High systolic blood pressure (SBP) was significantly correlated with a reduced cognitive functioning only in participants aged 70 years. Additionally, this correlation became more marked in participants with uncontrolled blood pressure at age 70 years. In contrast, SBP was not significantly correlated with the cognitive functioning at age 80 years. Nutritional status indicators such as serum albumin and frequency of going outdoors were significantly associated with cognitive functioning at age 80 years. Our findings indicate that high SBP has a significant role in cognitive functioning at age 70 years; however, blood pressure is less important as a risk factor for cognitive decline at age 80 years.
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