ArticleHypertension research : official journal of the Japanese Society of Hypertension2016
Left atrial dimension is related to blood pressure variability in newly diagnosed untreated hypertensive patients.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Left ventricular hypertrophy in association with cognitive impairment: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Pooled it
- Maximum home blood pressure readings are associated with left atrial diameter in essential hypertensives.Journal of human hypertension · 2018Trial
- Systolic Blood Pressure Variability and Outcomes in Atrial Fibrillation: A Nationwide Population Study in Korea.Journal of Korean medical science · 2026Article
- Within-visit and short- and long-term between-visit blood pressure variability as predictors of cardiovascular events and mortality in elderly Chinese.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Exploring the link between blood pressure variability and atrial fibrillation: current insights and future directions.Journal of human hypertension · 2024Review
- Greater nighttime blood pressure variability is associated with left atrial enlargement in atrial fibrillation patients with preserved ejection fraction.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- Arterial pressure lability is improved by sodium-glucose cotransporter 2 inhibitor in streptozotocin-induced diabetic rats.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
- Prevalence of prehypertension and left ventricular hypertrophy.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
- Relationships between 24-h blood pressure variability and 24-h central arterial pressure, pulse wave velocity and augmentation index in hypertensive patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
- Clinical and prognostic value of hypertensive cardiac damage in the PAMELA Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Review
- Left atrial dimension is related to blood pressure variability in newly diagnosed untreated hypertensive patients: methodological and statistical issues.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
- Response to Ayubi et al.: 'Left atrial dimension is related to blood pressure variability in newly diagnosed untreated hypertensive patients: methodological and statistical issues'.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
- Left atrial enlargement and blood pressure variability in untreated hypertensive patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Article
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3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Variability in daily blood pressure (BPV) recorded 24-h ambulatory blood pressure monitoring (ABPM) is known to be related to left ventricular hypertrophy and an increased incidence of cardiovascular events in hypertensive patients. The aim of this study was to evaluate whether left atrium dimension, which increases early in hypertensive subjects, was related to BPV in a group of 167 drug-naive patients (100M/67F, age: 46±11yr). The patients were chosen among those consecutively sent by their general practitioners to confirm the existence of arterial hypertension and afterwards diagnosed as hypertensive (mean 24-h ABPM ⩾130/80 mm Hg). In each patient, the left atrial posteroanterior diameter index for height (LADi) and the left ventricular mass standardized for body surface area (LVMi) were measured using standardized echocardiographic methods. BPV was calculated as the weighted mean of daytime and nighttime systolic and diastolic blood pressure s.d.'s (ws.d.), according to the formula ws.d.=[(daytime s.d. × 10)+nighttime s.d. × 6)]/16. An increase in left atrial dimension (LADi>24 mm m(-1)) was present in 36 patients (21.6% of the total population). In a univariate regression, LVMi was significantly related to systolic BPV (r=0.24; P=0.02) only in men, whereas LADi was significantly related to both systolic and diastolic BPV in both genders. After adjusting for sex, age, BMI, heart rate, diastolic function and estimated glomerular filtration rate, both systolic and diastolic BPV remained significantly related to LADi (P=0.02 for both) but not to LVMi. In conclusion, this study suggests that BVP, as measured as BPws.d., is significantly and independently associated with increased LADi in newly diagnosed, treatment-naive hypertensive patients.
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