Evidence map›Paper›PMID 27009416›Full record

ArticleCirculation. Arrhythmia and electrophysiology2016

Quantification of Left Ventricular Function With Premature Ventricular Complexes Reveals Variable Hemodynamics.

Francisco Contijoch, Kelly Rogers, Hannah Rears, Mohammed Shahid, Peter Kellman, Joseph Gorman, Robert C Gorman, Paul Yushkevich, Erica S Zado, Gregory E Supple and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation. Arrhythmia and electrophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. 2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2020
    Pooled it
  3. Article
  4. Article
  5. The future of CMR: All-in-one vs. real-time CMR (Part 2).Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024
    Review
  6. Review
  7. Review
  8. 2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2019
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Francisco ContijochFrom the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.). yuchi.han@uphs.upenn.edu.
Kelly RogersFrom the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.).
Hannah RearsFrom the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.).
Mohammed ShahidFrom the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.).
Peter KellmanFrom the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.).
Joseph GormanFrom the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.).
Robert C GormanFrom the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.).
Paul YushkevichFrom the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.).
Erica S ZadoFrom the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.).
Gregory E SuppleFrom the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.).
Francis E MarchlinskiFrom the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.).
Walter R T WitscheyFrom the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.).
Yuchi HanFrom the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.).
National Heart Lung and Blood Institute · US

Funding

Multidisciplinary Training in Cardiovascular BiologyT32HL007954 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI DAVIES, PETER FRANCIS · 2000 to 2019
$9.9M
Surgery to Prevent Post Infarction Ventricular RemodelingR01HL063954 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI GORMAN, ROBERT C · 2001 to 2018
$9.8M
Echocardiography to Predict Recurrent IMR After Surgical Mitral Valve ReplacementR01HL103723 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI GORMAN, ROBERT C, HUNG, JUDY W · 2011 to 2020
$5.3M
Training Program in Biomedical Imaging and Information SciencesT32EB009384 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI GEE, JAMES C, IVES, ZACHARY · 2009 to 2023
$4.0M
Adaptive Large-Scale Framework for Automatic Biomedical Image SegmentationR01EB017255 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI YUSHKEVICH, PAUL A. · 2014 to 2018
$3.0M
Continued Development and Maintenance of ITK-SNAP 3D Image Segmentation SoftwareR01EB014346 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI YUSHKEVICH, PAUL A. · 2011 to 2014
$2.0M
Nuclear Magnetic Tirho Relaxation in Acute and Chronic Myocardial InfarctionsR00HL108157 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WITSCHEY, WALTER R.T. · 2014 to 2016
$747k
Use of Real Time MRI for Evaluation of Regional Myocardial FunctionF31HL120580 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CONTIJOCH, FRANCISCO J · 2014 to 2015
$49k
NHLBI NIH HHS F31 HL120580NHLBI NIH HHS F31-HL120580NHLBI NIH HHS R00 HL108157NHLBI NIH HHS R00-HL108157NHLBI NIH HHS R01 HL063954NHLBI NIH HHS R01 HL103723NHLBI NIH HHS R01-HL103723NHLBI NIH HHS R01-HL63954NHLBI NIH HHS T32 HL007954NHLBI NIH HHS T32-HL007954NIBIB NIH HHS R01 EB014346NIBIB NIH HHS R01-EB014346NIBIB NIH HHS R01 EB017255NIBIB NIH HHS T32 EB009384NIBIB NIH HHS T32-EB009384
6 · The paper itself

Abstract

backgroundPremature ventricular complexes (PVCs) are prevalent in the general population and are sometimes associated with reduced ventricular function. Current echocardiographic and cardiovascular magnetic resonance imaging techniques do not adequately address the effect of PVCs on left ventricular function. METHODS AND

resultsFifteen subjects with a history of frequent PVCs undergoing cardiovascular magnetic resonance imaging had real-time slice volume quantification performed using a 2-dimensional (2D) real-time cardiovascular magnetic resonance imaging technique. Synchronization of 2D real-time imaging with patient ECG allowed for different beats to be categorized by the loading beat RR duration and beat RR duration. For each beat type, global volumes were quantified via summation over all slices covering the entire ventricle. Different patterns of ectopy, including isolated PVCs, bigeminy, trigeminy, and interpolated PVCs, were observed. Global functional measurement of the different beat types based on timing demonstrated differences in preload, stroke volume, and ejection fraction. An average of hemodynamic function was quantified for each subject depending on the frequency of each observed beat type.

conclusionsApplication of real-time cardiovascular magnetic resonance imaging in patients with PVCs revealed differential contribution of PVCs to hemodynamics.

Indexed as

ElectrocardiographyAdultAgedCardiac VolumeEchocardiographyFemaleHeart VentriclesHemodynamicsHumansImage Interpretation, Computer-AssistedMagnetic Resonance Imaging, CineMaleMiddle AgedProspective StudiesSeverity of Illness IndexStroke Volumecardiac arrhythmiasechocardiographymagnetic resonance imagingstroke volumeventricular premature complexes

Identifiers

PMID27009416
PMCPMC4807630
OpenAlexW2308537130

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.