ArticleScientific reports2016
The retinoid X receptor from mud crab: new insights into its roles in ovarian development and related signaling pathway.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 46 citations in OpenAlex.
- Dietary phosphatidylinositol promotes ovarian maturation in Pacific white shrimp (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Effects of All-Trans Retinoic Acid on Ovarian Development, Lipid Metabolism, Nutritional Quality, and Gut Microbiota of Female Chinese Mitten Crab During Fattening Period.International journal of molecular sciences · 2026Article
- Review
- Effects of Different Levels of Antarctic Krill Oil on the Ovarian Development ofAnimals : an open access journal from MDPI · 2024Article
- Comparative Transcriptome Analysis of Hepatopancreas Reveals Sexual Dimorphic Response to Methyl Farnesoate Injection inInternational journal of molecular sciences · 2024Article
- Comparative Study on Growth Index and Nutritional Quality of Female Chinese Mitten CrabAquaculture nutrition · 2023Article
- Fine sand facilitates egg extrusion and improves reproductive output in female mud crab genusPeerJ · 2022Article
- Evidences for Red Pigment Concentrating Hormone (Frontiers in endocrinology · 2021Article
- Article
- Identification, expression, and endocrine-disruption of three ecdysone-responsive genes in the sentinel species Gammarus fossarum.Scientific reports · 2018Article
- Comparative Transcriptome Analysis Provides Insights into Differentially Expressed Genes and Long Non-Coding RNAs between Ovary and Testis of the Mud Crab (Scylla paramamosain).Marine biotechnology (New York, N.Y.) · 2018Article
- Molecular Characterization and Expression Profiles of Sp-uchl3 and Sp-uchl5 during Gonad Development of Scylla paramamosain.Molecules (Basel, Switzerland) · 2018Article
- The current state of knowledge on the neuroactive compounds that affect the development, mating and reproduction of spiders (Araneae) compared to insects.Invertebrate neuroscience : IN · 2017Review
- Evolutionary Origin of the Interferon-Immune Metabolic Axis: The Sterol-Vitamin D Link.Frontiers in immunology · 2017Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In arthropods, retinoid X receptor (RXR) is a highly conserved nuclear hormone receptor. By forming a heterodimeric complex with the ecdysone receptor (EcR), RXR is known to be vital importance for various physiological processes. However, in comparison to EcR, the RXR signaling pathway and its roles in crustacean reproduction are poorly understood. In the present study, the RXR mRNA was detected in the ovarian follicular cells of mud crab Scylla paramamosain (SpRXR) and during ovarian maturation, its expression level was found to increase significantly. In vitro experiment showed that both SpRXR and vitellogenin (SpVg) mRNA in the ovarian explants were significantly induced by 20-hydroxyecdysone (20E) but not methyl farnesoate (MF). However, differing from the in vitro experiment, injection of MF in in vivo experiment significantly stimulated the expressions of SpRXR and SpVg in female crabs at early vitellogenic stage, but the ecdysone and insect juvenile hormone (JH) signaling pathway genes were not induced. The results together suggest that both MF and SpRXR play significant roles in regulating the expression of SpVg and ovarian development of S. paramamosain through their own specific signaling pathway rather than sharing with the ecdysone or the insect JH.
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