ArticlePloS one2016
Declining Trend of Hepatitis A Seroepidemiology in Association with Improved Public Health and Economic Status of Thailand.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- A randomized controlled trial of comparative effectiveness between the 2 dose and 3 dose regimens of hepatitis a vaccine in kidney transplant recipients.Scientific reports · 2021Trial
- Healthcare utilisation, expenditure, and admission-based mortality associated with paediatric hepatobiliary diseases in Thailand: a national database analysis (2015-2023).The Lancet regional health. Southeast Asia · 2026Article
- Seroprevalence of antibodies to hepatitis A, B and C viruses across all age groups in Chonburi Province, Thailand, 2022-2023.Human vaccines & immunotherapeutics · 2025Article
- Current Epidemiological Trends and Public Health Challenges of Hepatitis A Virus Infection in Thailand.The American journal of tropical medicine and hygiene · 2025Review
- Hepatitis A and E Virus Seroprevalence and Water, Sanitation and Hygiene Levels in Rural Areas of Khammouane Province, Lao People's Democratic Republic: A Cross-Sectional Study.Journal of medical virology · 2025Article
- Epstein-Barr Virus Seroprevalence in Thailand: A Temporal and Global Perspective with Health Care and Economic Correlations.The American journal of tropical medicine and hygiene · 2025Article
- Significant Reduction in Seroprevalence of Antibodies Against Hepatitis A across Thailand, 2024.The American journal of tropical medicine and hygiene · 2025Article
- Seroprevalence and Shifting Endemicities of Hepatitis A Virus Infection in Two Contrasting Geographical Areas in Indonesia.Medicina (Kaunas, Lithuania) · 2025Article
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- Hepatitis A vaccine immunogenicity among seronegative liver transplanted children.Scientific reports · 2024Article
- Seroprevalence and Shifting Endemicities of Hepatitis A Virus Infection in Two Different Geographical Areas in the Philippines.Infectious diseases and therapy · 2024Article
- Seroprevalence of hepatitis A virus antibodies among children and adolescents living in Northern Thailand: an implication for hepatitis A immunization.Scientific reports · 2023Article
- Impact of urbanization on morbidity of hepatitis A: a national panel study in China during 2005-2018.Infectious diseases of poverty · 2023Article
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- Eliminating viral hepatitis in children after liver transplants: How to reach the goal by 2030.World journal of gastroenterology · 2022Article
- Impact of Obesity and Being Overweight on the Immunogenicity to Live Attenuated Hepatitis A Vaccine in Children and Young Adults.Vaccines · 2021Article
- Towards the elimination of viral hepatitis in Thailand by the year 2030.Journal of virus eradication · 2020Review
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatitis A virus (HAV) is transmitted via the fecal-oral route from contaminated food or water. As part of the most recent survey of viral hepatitis burden in Thailand, we analyzed the current seroprevalence of HAV in the country and compared with data dating back to 1971. From March to October, 2014, a total of 4,260 individuals between one month and 71 years of age from different geographical regions (North = 961; Central = 1,125; Northeast = 1,109; South = 1,065) were screened for anti-HAV IgG antibody using an automated chemiluminescent microparticle immunoassay. Overall, 34.53% (1,471/4,260) possessed anti-HAV IgG antibody, and the age-standardized seroprevalence was 48.6%. Seroprevalence rates were 27.3% (North), 30.8% (Central), 33.8% (Northeast) and 45.8% (South) and were markedly lower than in the past studies especially among younger age groups. The overall trend showed an increase in the age by which 50% of the population were anti-HAV IgG antibody: 4.48 years (1971-1972), 6 (1976), 12.49 (1990), 36.02 (2004) and 42.03 (2014).This suggests that Thailand is transitioning from low to very low HAV endemicity. Lower prevalence of HAV correlated with improved healthcare system as measured by decreased infant mortality rate and improved national economy based on increased GDP per capita. The aging HAV immuno-naïve population may be rendered susceptible to potential HAV outbreaks similar to those in industrialized countries and may benefit from targeted vaccination of high-risk groups.
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