Evidence map›Paper›PMID 27008344›Full record

ArticleFood and environmental virology2016

Efficacy of Cinnamaldehyde Against Enteric Viruses and Its Activity After Incorporation Into Biodegradable Multilayer Systems of Interest in Food Packaging.

M J Fabra, J L Castro-Mayorga, W Randazzo, J M Lagarón, A López-Rubio, R Aznar, G Sánchez

Abstract read
PubMed Publisher
In one paragraph

Article in Food and environmental virology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Antiviral Activity of Natural Compounds for Food Safety.Food and environmental virology · 2024
    Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Air Disinfection-From Medical Areas to Vehicle.Frontiers in public health · 2022
    Article
  11. Natural Products and Their Potential Anti-HAV Activity.Pathogens (Basel, Switzerland) · 2021
    Review
  12. Opportunities for biomaterials to address the challenges of COVID-19.Journal of biomedical materials research. Part A · 2020
    Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Electrospun Nanofibres Containing Antimicrobial Plant Extracts.Nanomaterials (Basel, Switzerland) · 2017
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M J FabraFood Preservation and Food Quality Department, Institute of Agrochemistry and Food Technology (IATA-CSIC), Avda, Agustin Escardino 7, 46980, Paterna, Valencia, Spain.
J L Castro-MayorgaFood Preservation and Food Quality Department, Institute of Agrochemistry and Food Technology (IATA-CSIC), Avda, Agustin Escardino 7, 46980, Paterna, Valencia, Spain.
W RandazzoDepartment of Agricultural and Forest Science, University of Palermo, Palermo, Italy.
J M LagarónFood Preservation and Food Quality Department, Institute of Agrochemistry and Food Technology (IATA-CSIC), Avda, Agustin Escardino 7, 46980, Paterna, Valencia, Spain.
A López-RubioFood Preservation and Food Quality Department, Institute of Agrochemistry and Food Technology (IATA-CSIC), Avda, Agustin Escardino 7, 46980, Paterna, Valencia, Spain.
R AznarBiotechnology Department, IATA-CSIC, Avda. Agustín Escardino 7, 46980, Paterna, Valencia, Spain.
G SánchezBiotechnology Department, IATA-CSIC, Avda. Agustín Escardino 7, 46980, Paterna, Valencia, Spain. gloriasanchez@iata.csic.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cinnamaldehyde (CNMA), an organic compound that gives cinnamon its flavor and odor, was investigated for its virucidal activity on norovirus surrogates, murine norovirus (MNV) and feline calicivirus (FCV), and hepatitis A virus (HAV). Initially, different concentrations of CNMA (0.1, 0.5 and 1 %) were individually mixed with each virus at titers of ca. 6-7 log10 TCID50/ml and incubated 2 h at 4 and 37 °C. CNMA was effective in reducing the titers of norovirus surrogates in a dose-dependent manner after 2 h at 37 °C, while HAV titers were reduced by 1 log10 after treatment with 1 % of CNMA. When incubation time was extended, HAV titers were reduced by 3.4 and 2.7 log10 after overnight incubation at 37 °C with 1 and 0.5 % of CNMA, respectively. Moreover, this paper analyzed, for the first time, the antiviral activity of adding an active electrospun interlayer based on zein and CNMA to a polyhydroxybutyrate packaging material (PHB) in a multilayer form. Biodegradable multilayer systems prepared with 2.60 mg/cm(2) (~9.7 %) of CNMA completely inactivated FCV according to ISO 22196:2011, while MNV titers were reduced by 2.75 log10. When the developed multilayer films were evaluated after one month of preparation or at 25 °C, the antiviral activity was reduced as compared to freshly prepared multilayer films evaluated at 37 °C. The results show the excellent potential of this system for food contact applications as well as for active packaging technologies in order to maintain or extend food quality and safety.

Indexed as

AcroleinAnimalsCalicivirus, FelineCatsDisinfectantsFood ContaminationFood PackagingHepatitis A virusHumansMiceNorovirusPaperProhibitinsVirus InactivationAcroleincinnamaldehydeDisinfectantsPHB protein, humanProhibitinsActive packagingCinnamaldehydeEnteric virusesMultilayer structures

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.