Evidence map›Paper›PMID 27007988›Full record

ReviewCurrent treatment options in neurology2016

Behçet's Disease and Nervous System Involvement.

Murat Kürtüncü, Erdem Tüzün, Gulsen Akman-Demir

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current treatment options in neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Neuro-behcet's syndrome: epidemiology, mechanisms, and emerging strategies in diagnosis and treatment.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Behçet's Disease in Children: Diagnostic and Management Challenges.Therapeutics and clinical risk management · 2020
    Review
  8. Review
  9. Article
  10. Wrist Drop as a Manifestation of Behçet's Disease.European journal of case reports in internal medicine · 2017
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Murat KürtüncüIstanbul Faculty of Medicine, Department of Neurology, Istanbul University, Istanbul, Turkey.
Erdem TüzünInstitute of Experimental Medicine and Research, Department of Neuroscience, Istanbul University, Istanbul, Turkey.
Gulsen Akman-DemirSchool of Medicine, Department of Neurology, Istanbul Bilim (Science) University, Istanbul, Turkey. akmandemir@yahoo.com.
Istanbul University · TRIstanbul Bilim University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

opinion statementManagement of neuro-Behçet's disease can be divided into two stages: treatment of acute attacks and prevention of relapses. Treatment of acute attacks is accomplished by high-dose intravenous corticosteroids followed by maintenance treatment with oral steroids for 6-12 months depending on the type and severity of the neurological involvement. Relapses can be prevented by using immunosuppressants. Oral immunosuppressants such as azathioprine and mycophenolate are the most widely utilized agents for this purpose. Patients who are refractory or who cannot tolerate these medications can be managed by cyclophosphamide, interferon alpha, or anti-TNF-α monoclonal antibodies such as infliximab, etanercept, and adalimumab. Recent reports showed that newer agents such as tocilizumab, canakinumab, and anakinra, which exert their biological activity through IL-1 and IL-6 pathways, are also promising treatment alternatives for progressive or relapsing patients.

Indexed as

Autoinflammatory disorderBehçet’s diseaseImmunosuppressionNeuro-Behçet’s diseaseTreatment

Identifiers

PMID27007988
OpenAlexW2305341806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.