ArticleMucosal immunology2016
Interleukin-22 regulates antimicrobial peptide expression and keratinocyte differentiation to control Staphylococcus aureus colonization of the nasal mucosa.
Article in Mucosal immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 56 citations in OpenAlex.
- Role and plasticity of Th1 and Th17 responses in immunity toHuman vaccines & immunotherapeutics · 2019Trial
- IL-22Ra2 Levels Remain Elevated in People with Cystic Fibrosis despite Modulator Therapy.American journal of respiratory and critical care medicine · 2024Article
- Type 1 interferons promote Staphylococcus aureus nasal colonization by inducing phagocyte apoptosis.Cell death discovery · 2024Article
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- Nanoparticles ofNutrients · 2023Article
- Advanced In Vitro Three-Dimensional Skin Models of Atopic Dermatitis.Tissue engineering and regenerative medicine · 2023Review
- Chemerin Exacerbates Psoriasis by Stimulating Keratinocyte Proliferation and Cytokine Production.Current medical science · 2023Article
- Crosstalk between the gut microbiota and innate lymphoid cells in intestinal mucosal immunity.Frontiers in immunology · 2023Review
- γδ T cell-intrinsic IL-1R promotes survival duringFrontiers in immunology · 2023Article
- Chronic stress induces colonic tertiary lymphoid organ formation and protection against secondary injury through IL-23/IL-22 signaling.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Potential Therapeutic Skin Microbiomes SuppressingInternational journal of molecular sciences · 2022Article
- Staphylococcus aureus-induced immunosuppression mediated by IL-10 and IL-27 facilitates nasal colonisation.PLoS pathogens · 2022Article
- ATF3 Positively Regulates Antibacterial Immunity by Modulating Macrophage Killing and Migration Functions.Frontiers in immunology · 2022Article
- Loss of aryl hydrocarbon receptor suppresses the response of colonic epithelial cells to IL22 signaling by upregulating SOCS3.American journal of physiology. Gastrointestinal and liver physiology · 2022Article
- Host factors facilitating SARS-CoV-2 virus infection and replication in the lungs.Cellular and molecular life sciences : CMLS · 2021Review
- Article
- Article
- Molecular Level Insights Into the Structural and Dynamic Factors Driving Cytokine Function.Frontiers in molecular biosciences · 2021Review
- Boosting the IL-22 response using flagellin prevents bacterial infection in cigarette smoke-exposed mice.Clinical and experimental immunology · 2020Article
- The Dichotomous Responses Driven by β-Defensins.Frontiers in immunology · 2020Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The local immune response occurring during Staphylococcus aureus nasal colonization remains ill-defined. Studies have highlighted the importance of T-cell immunity in controlling S. aureus colonization of the nasal mucosa. We extend these observations, identifying a critical role for interleukin (IL)-22 in this process. IL-22 is basally expressed within the nasal mucosa and is induced upon S. aureus colonization. IL-22 is produced by CD4+ and CD8+ T lymphocytes at this site, with innate-like lymphocytes also contributing. IL-22
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.