SynthesisInternational urology and nephrology2016
Testicular microlithiasis and testicular cancer: review of the literature.
Synthesis in International urology and nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- The role of the radiologist in the evaluation of male infertility: recommendations of the European Society of Urogenital Radiology-Scrotal and Penile Imaging Working Group (ESUR-SPIWG) for scrotal imaging.European radiology · 2025Guideline
- Article
- Development and Validation of an Ultrasound Imaging Algorithm for Structured Reporting in Testicular Pathology.Diagnostics (Basel, Switzerland) · 2025Article
- Association of testicular calcifications and intracranial germinoma: a case report and review of the literature.Translational pediatrics · 2025Article
- Article
- An Insight into Testicular Macrocalcification-A Retrospective Study of 42 Cases on a Rare Sonographic Finding.Life (Basel, Switzerland) · 2025Article
- Management of pediatric testicular microlithiasis.Frontiers in pediatrics · 2025Review
- Is testicular microlithiasis associated with decreased semen parameters? a systematic review.Basic and clinical andrology · 2024Review
- Kidney and urological involvement in Down syndrome: frequent, underestimated, but associated with impaired quality of life and risk of kidney failure.Pediatric nephrology (Berlin, Germany) · 2024Review
- Testicular mass with macrocalcification and osseous metaplasia: A case report.SAGE open medical case reports · 2024Article
- A survey of testicular texture in canine ultrasound images.Frontiers in veterinary science · 2023Article
- The burden of testicular cancer from 1990 to 2019 in the Middle East and North Africa region.Frontiers in oncology · 2023Article
- Evaluation of selected semen parameters and biomarkers of male infertility - preliminary study.F1000Research · 2022Article
- Article
- Lack of pathogenic germline DICER1 variants in males with testicular germ-cell tumors.Cancer genetics · 2020Article
- Testicular ultrasound score: A new proposal for a scoring system to predict testicular function.Andrology · 2020Article
- Identification of potential core genes and miRNAs in testicular seminoma via bioinformatics analysis.Molecular medicine reports · 2019Article
- Association between risk factors and testicular microlithiasis.Acta radiologica open · 2019Article
- Testicular microlithiasis and testicular tumor: a review of the literature.Basic and clinical andrology · 2018Article
- Characteristics of symptomatic men with testicular microlithiasis - A Danish cross-sectional questionnaire study.Andrology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo perform a systematic literature review to assess whether the occurrence of testicular microlithiasis (TML) in conjunction with other risk factors is associated with testicular cancer.
methodsA systematic literature search was performed of original articles in English published 1998 to 2015. Relevant studies were selected by reading the title and abstract by two of the authors. Studies were included if TML was diagnosed by ultrasonography and a risk condition was reported. Studies were only eligible if the particular risk condition was reported in more than one article.
resultsIn total, 282 abstracts in were identified. Based on title and abstract the eligibility was assessed and 31 studies were included. Five conditions in relation to TML and testicular cancer emerged: Down syndrome, McCune-Albright syndrome, cryptorchidism, infertility and familial disposition of testicular cancer.
conclusionData support the conclusion that TML is not an independent risk factor for testicular cancer but associated with testicular cancer through other conditions. In male infertility, TML appears to be related to an increased risk of testicular cancer possibly as part of a testicular dysgenesis syndrome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.