Evidence map›Paper›PMID 27007563›Full record

ArticleRevista do Instituto de Medicina Tropical de Sao Paulo2016

AMERICAN CUTANEOUS LEISHMANIASIS WITH UNUSUAL CLINICAL PRESENTATION AND RESPONSE TO TREATMENT.

Andrea Claudia Bekner Silva Fernandes, Raíssa Bocchi Pedroso, Eneide Aparecida Sabaini Venazzi, Paulo Donizeti Zanzarini, Sandra Mara Alessi Aristides, Maria Valdrinez Campana Lonardoni, Thaís Gomes Verzignassi Silveira

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Revista do Instituto de Medicina Tropical de Sao Paulo, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Case Report: Atypical Cutaneous Leishmaniasis in a Patient with MixedThe American journal of tropical medicine and hygiene · 2018
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Andrea Claudia Bekner Silva FernandesPrograma de Pós-Graduação em Ciências da Saúde, Universidade Estadual de Maringá, Maringá, Paraná, Brasil, acbsfernandes@gmail.com, raissap@gmail.com.
Raíssa Bocchi PedrosoPrograma de Pós-Graduação em Ciências da Saúde, Universidade Estadual de Maringá, Maringá, Paraná, Brasil, acbsfernandes@gmail.com, raissap@gmail.com.
Eneide Aparecida Sabaini VenazziDepartamento de Análises Clínicas e Biomedicina, Universidade Estadual de Maringá, Maringá, Paraná, Brasil, easvenazzi@uem.br, pdzanzarini@uem.br, smaaristides@uem.br, mvclonardoni@uem.br, tgvsilveira@uem.br.
Paulo Donizeti ZanzariniDepartamento de Análises Clínicas e Biomedicina, Universidade Estadual de Maringá, Maringá, Paraná, Brasil, easvenazzi@uem.br, pdzanzarini@uem.br, smaaristides@uem.br, mvclonardoni@uem.br, tgvsilveira@uem.br.
Sandra Mara Alessi AristidesDepartamento de Análises Clínicas e Biomedicina, Universidade Estadual de Maringá, Maringá, Paraná, Brasil, easvenazzi@uem.br, pdzanzarini@uem.br, smaaristides@uem.br, mvclonardoni@uem.br, tgvsilveira@uem.br.
Maria Valdrinez Campana LonardoniDepartamento de Análises Clínicas e Biomedicina, Universidade Estadual de Maringá, Maringá, Paraná, Brasil, easvenazzi@uem.br, pdzanzarini@uem.br, smaaristides@uem.br, mvclonardoni@uem.br, tgvsilveira@uem.br.
Thaís Gomes Verzignassi SilveiraDepartamento de Análises Clínicas e Biomedicina, Universidade Estadual de Maringá, Maringá, Paraná, Brasil, easvenazzi@uem.br, pdzanzarini@uem.br, smaaristides@uem.br, mvclonardoni@uem.br, tgvsilveira@uem.br.
Universidade Estadual de Maringá · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical manifestations and prognosis of cutaneous leishmaniasis (CL) can be influenced by the immune response of the patient and the species of the parasite. A case of atypical clinical presentation of CL, with development of non-characteristic lesions, poor response to therapy, and a long time to resolution is reported. Confirmatory laboratory tests included parasite detection, indirect immunofluorescence, Montenegro skin test, polymerase chain reaction, and parasite identification by multilocus enzyme electrophoresis. The parasite was identified as Leishmania braziliensis. The lesion was unresponsive to three complete courses of N-methylglucamine antimoniate intramuscular, and to treatment with pentamidine. The patient did not tolerate amphotericin B. The lesion finally receded after treatment with intravenous N-methylglucamine antimoniate. It is essential to ensure the accuracy of diagnosis and the appropriate treatment, which can include the use a second choice drug or a different route of administration.

Indexed as

Leishmania braziliensisAmphotericin BHumansLeishmaniasis, CutaneousMaleMeglumineMeglumine AntimoniateMiddle AgedOrganometallic CompoundsTreatment OutcomeAmphotericin BMeglumineMeglumine AntimoniateOrganometallic Compounds

Identifiers

PMID27007563
PMCPMC4804557
OpenAlexW2305168406

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.