ArticleRevista do Instituto de Medicina Tropical de Sao Paulo2016
ANTIFUNGAL POTENTIAL OF PLANT SPECIES FROM BRAZILIAN CAATINGA AGAINST DERMATOPHYTES.
Article in Revista do Instituto de Medicina Tropical de Sao Paulo, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Mechanism of action and synergistic effect of Eugenia uniflora extract in Candida spp.PloS one · 2024Article
- Incidence of Shiga toxin-producingCanadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2021Article
- In vitro antidermatophytic activity of bioactive compounds from selected medicinal plants.Journal of analytical science and technology · 2021Article
- Antifungal Combination of Ethyl Acetate Extract ofFrontiers in microbiology · 2021Article
- Antifungal and Antibiofilm Activities of B-Type Oligomeric Procyanidins FromFrontiers in microbiology · 2021Article
- Review
- Traditional Herbal Medicine in Mesoamerica: Toward Its Evidence Base for Improving Universal Health Coverage.Frontiers in pharmacology · 2020Review
- Influence of Eugenia uniflora Extract on Adhesion to Human Buccal Epithelial Cells, Biofilm Formation, and Cell Surface Hydrophobicity of Candida spp. from the Oral Cavity of Kidney Transplant Recipients.Molecules (Basel, Switzerland) · 2018Article
- Virulence Inhibitors from Brazilian Peppertree Block Quorum Sensing and Abate Dermonecrosis in Skin Infection Models.Scientific reports · 2017Article
- Effect of the Ethyl Acetate Fraction ofFrontiers in microbiology · 2017Article
- Spectrophotometric Quantification of Flavonoids in Herbal Material, Crude Extract, and Fractions from Leaves ofPharmacognosy researchArticle
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Authors and funding
8 authors.
Funding
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Abstract
Trichophyton rubrum and Trichophyton mentagrophytes complex, or Trichophyton spp. are the main etiologic agents of dermatophytosis, whose treatment is limited by the high cost of antifungal treatments, their various side effects, and the emergence of resistance amongst these species. This study evaluated the in vitro antidermatophytic activity of 23 crude extracts from nine plant species of semiarid vegetation (caatinga) found in Brazil. The extracts were tested at concentrations ranging from 1.95 to 1,000.0 mg/mL by broth microdilution assay against the reference strains T. rubrum ATCC 28189 and T. mentagrophytes ATCC 11481, and 33 clinical isolates of dermatophytes. All plants showed a fungicidal effect against both fungal species, with MIC/MFC values of the active extracts ranging from 15.6 to 250.0 µg/mL. Selected extracts of Eugenia uniflora (AcE), Libidibia ferrea (AE), and Persea americana (AcE) also exhibited a fungicidal effect against all clinical isolates of T. rubrum and T. mentagrophytes complex. This is the first report of the antifungal activity of Schinus terebinthifolius, Piptadenia colubrina, Parapiptadenia rigida, Mimosa ophthalmocentra, and Persea americana against both dermatophyte species.
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