Evidence map›Paper›PMID 27007272›Full record

Trial reportObesity surgery2016

Intraperitoneal Ropivacaine Irrigation in Patients Undergoing Bariatric Surgery: a Prospective Randomized Clinical Trial.

Jaime Ruiz-Tovar, Juan Gonzalez, Alejandro Garcia, Consuelo Cruz, Sara Rivas, Montiel Jimenez, Carlos Ferrigni, Manuel Duran

4 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Obesity surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02641288 phase3completednot on this map

Intraperitoneal Ropivacaine Irrigation in Patients Undergoing Bariatric Surgery

TypeinterventionalSponsorHospital General Universitario ElcheRan2015 to 2015Enrolled110ConditionsPainArmsRopivacaine irrigation, Normal saline irrigation
NCT03175081 nacompletednot on this mapstarted 2017, after this paper: background citation

Intraperitoneal Local Anesthetic in Bariatric Surgery: A Double Blind-randomized Controlled Pilot Trial

TypeinterventionalSponsorDr. Tikfu GeeRan2017 to 2018Enrolled54ConditionsOverweight and Obesity, Bariatric Surgery CandidateArmsRopivacaine, Normal saline
NCT06145945 naunknown statusnot on this mapstarted 2023, after this paper: background citation

A Randomized Controlled Study of the Effect of Intraperitoneal Ropivacaine on Visceral Pain After Laparoscopic Gastrectomy

TypeinterventionalSponsorSanQing JinRan2023 to 2024Enrolled72ConditionsLaparoscopic Gastrectomy, RopivacaineArms0.5% Ropivacaine, Saline
NCT07400146 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Instillation of Bupivacaine With Epinephrine Over Diaphragm to Reduce Postoperative Shoulder Pain Following Benign Gynecologic Laparoscopic Surgery: A Randomized Control Trial

TypeinterventionalSponsorCedars-Sinai Medical CenterRan2026 to 2026Enrolled100ConditionsPostoperative Pain, Shoulder PainArmsInstillation of Bupivacaine with epinephrine over the diaphragm
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jaime Ruiz-TovarUniversity Hospital Rey Juan Carlos, Mostoles, Madrid, Spain. jruiztovar@gmail.com.
Juan GonzalezUniversity Hospital Rey Juan Carlos, Mostoles, Madrid, Spain.
Alejandro GarciaUniversity Hospital Rey Juan Carlos, Mostoles, Madrid, Spain.
Consuelo CruzUniversity Hospital Rey Juan Carlos, Mostoles, Madrid, Spain.
Sara RivasUniversity Hospital Rey Juan Carlos, Mostoles, Madrid, Spain.
Montiel JimenezUniversity Hospital Rey Juan Carlos, Mostoles, Madrid, Spain.
Carlos FerrigniUniversity Hospital Rey Juan Carlos, Mostoles, Madrid, Spain.
Manuel DuranUniversity Hospital Rey Juan Carlos, Mostoles, Madrid, Spain.
Hospital Universitario Rey Juan Carlos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite most bariatric procedures are actually performed by laparoscopic approach, management of postoperative pain remains a major challenge. The aim of this study was to analyze the analgesic effect of intraperitoneal ropivacaine infusion in patients undergoing bariatric surgery.

methodsA prospective randomized clinical trial of all the patients undergoing laparoscopic sleeve gastrectomy (LSG) or laparoscopic Roux-en-Y gastric bypass (LRYGB) between January and November 2015 was performed. Patients were randomized to experimental (EG: those patients undergoing intraperitoneal ropivacain irrigation) and control groups (CG: those undergoing intraperitoneal irrigation with normal saline).

resultsOne hundred ten patients were included, 83 LRYGB (75.5 %) and 27 LSG (24.5 %). Mean pain, as measured by VAS score, was 21.7 ± 14.5 mm in CG and 13.3 ± 10.9 mm in EG (p = 0.002). Morphine needs during the first 24 h postoperatively were 21.8 % in CG and 3.6 % in EG (p = 0.01). Early taking of fluids by mouth was possible 6 h after surgery in 76.4 % in EG vs 34.5 % in CG (p = 0.001). Early mobilization ability (6 h after surgery) was feasible in 72.7 % in EG and 32.7 % in CG (p = 0.001). Median hospital stay was 3 days (range 2-10 days) in CG and 2 days (2-7 days) in EG (p = 0.009).

conclusionsThe intraoperative peritoneal infusion with ropivacaine in patients undergoing bariatric surgery is associated with a reduction in postoperative pain, lower morphine needs, earlier mobilization and earlier oral intake of fluids after surgery, and a shorter hospital stay. ClinicalTrials.gov Identifier: NCT02641288.

Indexed as

Bariatric SurgeryAdultAmidesAnesthetics, LocalFemaleHumansInfusions, ParenteralLaparoscopyMaleMiddle AgedObesityPeritoneal LavagePostoperative PainProspective StudiesRopivacaineAmidesAnesthetics, LocalRopivacaineBariatric surgeryIntraperitoneal irrigationPostoperative painRopivacaine

Identifiers

PMID27007272
OpenAlexW2305672096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.