ArticleAmerican journal of respiratory and critical care medicine2016
Pulmonary Abnormalities in Young, Light-Use Waterpipe (Hookah) Smokers.
Article in American journal of respiratory and critical care medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Determining the perceived risk of lung cancer and chronic obstructive pulmonary diseases (COPD) among hookah users in Iran.BMC pulmonary medicine · 2024Article
- Medical Trainees' Knowledge and Attitudes Towards Electronic Cigarettes and Hookah: A Multinational Survey Study.Respiratory care · 2024Article
- Exploring motivation to quit and risk appraisals of hookah tobacco smoking for self and partner among a member of single and dual smoker couples.Journal of behavioral medicine · 2023Article
- Waterpipe smoking: Results from a population-based study in Qatar.Tobacco induced diseases · 2022Article
- The adverse health effects of waterpipe smoking in adolescents and young adults: A narrative review.Tobacco induced diseases · 2021Review
- Exosomal microRNAs are novel circulating biomarkers in cigarette, waterpipe smokers, E-cigarette users and dual smokers.BMC medical genomics · 2020Article
- Measuring waterpipe tobacco smoking in survey research.Tobacco control · 2020Article
- Swimming Exercise Training Attenuates the Lung Inflammatory Response and Injury Induced by Exposing to Waterpipe Tobacco Smoke.Addiction & health · 2020Article
- The effects of hookah/waterpipe smoking on general health and the cardiovascular system.Environmental health and preventive medicine · 2019Review
- A COmplex Cloud.Circulation · 2019Article
- Respiratory health and quality of life in young exclusive, habitual smokers - a comparison of waterpipe smokers, cigarette smokers and non-smokers.International journal of chronic obstructive pulmonary disease · 2019Article
- Airway reactivity to mannitol is similarly increased in chronic cigarette and water pipe smokers.International journal of chronic obstructive pulmonary disease · 2018Observational
- Increasing popularity of waterpipe tobacco smoking and electronic cigarette use: Implications for oral healthcare.Journal of periodontal research · 2017Review
- Toxicological impact of waterpipe smoking and flavorings in the oral cavity and respiratory system.Inhalation toxicology · 2017Review
- Water-pipe smoke condensate increases the internalization of Mycobacterium Bovis of type II alveolar epithelial cells (A549).BMC pulmonary medicine · 2017Article
- Article
- Increased airway resistance among exclusive waterpipe smokers detected using impulse oscillometry.Annals of thoracic medicineArticle
Corrections and comments
- Commented on by
Authors and funding
19 authors.
Funding
Abstract
rationaleWaterpipes, also called hookahs, are currently used by millions of people worldwide. Despite the increasing use of waterpipe smoking, there is limited data on the health effects of waterpipe smoking and there are no federal regulations regarding its use.
objectivesTo assess the effects of waterpipe smoking on the human lung using clinical and biological parameters in young, light-use waterpipe smokers.
methodsWe assessed young, light-use, waterpipe-only smokers in comparison with lifelong nonsmokers using clinical parameters of cough and sputum scores, lung function, and chest high-resolution computed tomography as well as biological parameters of lung epithelial lining fluid metabolome, small airway epithelial (SAE) cell differential and transcriptome, alveolar macrophage transcriptome, and plasma apoptotic endothelial cell microparticles. MEASUREMENTS AND MAIN
resultsCompared with nonsmokers, waterpipe smokers had more cough and sputum as well as a lower lung diffusing capacity, abnormal epithelial lining fluid metabolome profile, increased proportions of SAE secretory and intermediate cells, reduced proportions of SAE ciliated and basal cells, markedly abnormal SAE and alveolar macrophage transcriptomes, and elevated levels of apoptotic endothelial cell microparticles.
conclusionsYoung, light-use, waterpipe-only smokers have a variety of abnormalities in multiple lung-related biological and clinical parameters, suggesting that even limited waterpipe use has broad consequences on human lung biology and health. We suggest that large epidemiological studies should be initiated to investigate the harmful effects of waterpipe smoking.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.