SynthesisRevista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)2016
Neurobiological underpinnings of bipolar disorder focusing on findings of diffusion tensor imaging: a systematic review.
Synthesis in Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 36 citations in OpenAlex.
- Altered white matter integrity in pediatric bipolar disorder and the potential role of psychotic symptoms revealed by free water elimination corrected and superficial white matter DTI analyses.European child & adolescent psychiatry · 2026Article
- Article
- Comprehensive assessment of sleep duration, insomnia, and brain structure within the UK Biobank cohort.Sleep · 2024Article
- Lower serum insulin-like growth factor 2 level in patients with bipolar disorder is associated with the severity of manic symptoms during manic episodes.Frontiers in psychiatry · 2024Article
- Microstructural Changes in the Cerebral White Matter After 12 Months of CPAP Treatment for Moderate to Severe Obstructive Sleep Apnoea: A TBSS Study.Nature and science of sleep · 2024Article
- Bipolar disorder: an association between body mass index and cingulate gyrus fractional anisotropy not mediated by systemic inflammation.Trends in psychiatry and psychotherapy · 2022Article
- White matter microstructure associated with anhedonia among individuals with bipolar disorders and high-risk for bipolar disorders.Journal of affective disorders · 2022Article
- Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): III. Emotional dysfunction superspectrum.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022Article
- Age-related white matter changes revealed by a whole-brain fiber-tracking method in bipolar disorder compared to major depressive disorder and healthy controls.Psychiatry and clinical neurosciences · 2021Article
- Neuroanatomic and Functional Neuroimaging Findings.Current topics in behavioral neurosciences · 2021Article
- Comparison of White Matter Structure of Drug-Naïve Patients With Bipolar Disorder and Major Depressive Disorder Using Diffusion Tensor Tractography.Frontiers in psychiatry · 2021Article
- White matter abnormalities and cognitive function in euthymic patients with bipolar disorder and major depressive disorder.Brain and behavior · 2020Article
- Neuroinflammation in Bipolar Depression.Frontiers in psychiatry · 2020Review
- A Connectomic Atlas of the Human Cerebrum-Chapter 17: Tractographic Description of the Cingulum.Operative neurosurgery (Hagerstown, Md.) · 2018Article
- Aberrant Anterior Thalamic Radiation Structure in Bipolar Disorder: A Diffusion Tensor Tractography Study.Frontiers in psychiatry · 2018Article
- Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Review
- Psychosis: glia, immunity, and melatonin.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Article
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo review the available data on diffusion tensor imaging (DTI) of subjects with bipolar disorder (BD), with a particular focus on fractional anisotropy (FA) in white matter (WM) tracts.
methodsThe PubMed/MEDLINE database was searched for relevant articles, which were included in a systematic review of the literature. FA reductions and WM abnormalities were divided anatomically into three groups: commissural tracts, association tracts, and projection tracts.
resultsEighteen studies met the inclusion criteria. The corpus callosum was the main impaired commissural tract as demonstrated by FA reductions. Five studies reported FA reductions in the cingulum. Two studies reported decreased FA in the anterior thalamic radiation, and one in the corticospinal tract. Conversely, three studies found increased FA values in WM tracts involved in BD pathophysiology.
conclusionDespite considerable heterogeneity, these results indicate a direct link between executive cognitive functioning and abnormal WM microstructural integrity of fronto-limbic tracts in patients with remitted BD, providing further evidence of the neuronal disruption that underlies BD symptomatology.
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