Evidence map›Paper›PMID 27006781›Full record

ArticleCanadian journal of kidney health and disease2016

Comparative effectiveness of home dialysis therapies: a matched cohort study.

Gihad E Nesrallah, Lihua Li, Rita S Suri

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian journal of kidney health and disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Cost of the quanta SC+ hemodialysis system for self-care in the United Kingdom.Hemodialysis international. International Symposium on Home Hemodialysis · 2022
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Gihad E NesrallahThe Li Ka Shing Knowledge Institute, Keenan Research Center, St. Michael's Hospital, 30 Bond Street, Toronto, Ontario M5B 1W8 Canada ; Nephrology Program, Humber River Regional Hospital, Toronto, Ontario Canada ; Division of Nephrology, Western University, London, Ontario Canada.
Lihua LiDivision of Nephrology, Western University, London, Ontario Canada.
Rita S SuriDivision of Nephrology, Western University, London, Ontario Canada ; Centre de Recherche, Centre Hospitalier de l'Université de Montréal, Montréal, Québec Canada.
Centre Hospitalier de l’Université de Montréal · CASt. Michael's Hospital · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHome dialysis is being increasingly promoted among patients with end-stage renal disease, but the comparative effectiveness of home hemodialysis and peritoneal dialysis is unknown.

objectiveTo determine whether patients receiving home daily hemodialysis have reduced mortality risk compared with matched patients receiving home peritoneal dialysis.

designThis study is an observational, propensity-matched, new-user cohort study.

settingLinked electronic data were from the United States Renal Data System (USRDS) and a large dialysis provider's database. PATIENTS: The patients were adults receiving in-center hemodialysis in the USA between 2004 and 2011 and registered in the USRDS. MEASUREMENTS: Baseline comorbidities, demographics, and outcomes for both groups were ascertained from the United States Renal Data System.

methodsWe identified 3142 consecutive adult patients initiating home daily hemodialysis (≥5 days/week for ≥1.5 h/day) and matched 2688 of them by propensity score to 2688 contemporaneous US patients initiating home peritoneal dialysis. We used Cox regression to compare all-cause mortality between groups.

resultsAfter matching, the two groups were well balanced on all baseline characteristics. Mean age was 51 years, 66 % were male, 72 % were white, and 29 % had diabetes. During 10,221 patient-years of follow-up, 1493/5336 patients died. There were significantly fewer deaths among patients receiving home daily hemodialysis than those receiving peritoneal dialysis (12.7 vs 16.7 deaths per 100 patient-years, respectively; hazard ratio (HR) 0.75; 95 % CI 0.68-0.82; p < 0.001). Similar results were noted with several different analytic methods and for all pre-specified subgroups. LIMITATIONS: We cannot exclude residual confounding in this observational study.

conclusionsHome daily hemodialysis was associated with lower mortality risk than home peritoneal dialysis.

Identifiers

PMID27006781
PMCPMC4802626
OpenAlexW2308276172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.