Evidence map›Paper›PMID 27006678›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2016

Antimutagenic Compounds of White Shrimp (Litopenaeus vannamei): Isolation and Structural Elucidation.

Carmen-María López-Saiz, Javier Hernández, Francisco-Javier Cinco-Moroyoqui, Carlos Velázquez, Víctor-Manuel Ocaño-Higuera, Maribel Plascencia-Jatomea, Maribel Robles-Sánchez, Lorena Machi-Lara, Armando Burgos-Hernández

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carmen-María López-SaizDepartamento de Investigación y Posgrado en Alimentos, Universidad de Sonora, Apartado Postal 1658, 83000 Hermosillo, SON, Mexico; Programa de Ingeniería Ambiental, Universidad Estatal de Sonora, 83000 Hermosillo, SON, Mexico.
Javier HernándezUnidad de Servicios de Apoyo en Resolución Analítica, Universidad Veracruzana, 91240 Xico, VER, Mexico.
Francisco-Javier Cinco-MoroyoquiDepartamento de Investigación y Posgrado en Alimentos, Universidad de Sonora, Apartado Postal 1658, 83000 Hermosillo, SON, Mexico.
Carlos VelázquezDepartamento de Ciencias Químico-Biológicas, Universidad de Sonora, 83000 Hermosillo, SON, Mexico.
Víctor-Manuel Ocaño-HigueraDepartamento de Ciencias Químico-Biológicas, Universidad de Sonora, 83000 Hermosillo, SON, Mexico.
Maribel Plascencia-JatomeaDepartamento de Investigación y Posgrado en Alimentos, Universidad de Sonora, Apartado Postal 1658, 83000 Hermosillo, SON, Mexico.
Maribel Robles-SánchezDepartamento de Investigación y Posgrado en Alimentos, Universidad de Sonora, Apartado Postal 1658, 83000 Hermosillo, SON, Mexico.
Lorena Machi-LaraDepartamento de Investigación en Polímeros y Materiales, Universidad de Sonora, 83000 Hermosillo, SON, Mexico.
Armando Burgos-HernándezDepartamento de Investigación y Posgrado en Alimentos, Universidad de Sonora, Apartado Postal 1658, 83000 Hermosillo, SON, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the World Health Organization, cancer is the main cause of mortality worldwide; thus, the search of chemopreventive compounds to prevent the disease has become a priority. White shrimp (Litopenaeus vannamei) has been reported as a source of compounds with chemopreventive activities. In this study, shrimp lipids were extracted and then fractionated in order to isolate those compounds responsible for the antimutagenic activity. The antimutagenic activity was assessed by the inhibition of the mutagenic effect of aflatoxin B1 on TA98 and TA100 Salmonella tester strains using the Ames test. Methanolic fraction was responsible for the highest antimutagenic activity (95.6 and 95.9% for TA98 and TA100, resp.) and was further separated into fifteen different subfractions (M1-M15). Fraction M8 exerted the highest inhibition of AFB1 mutation (96.5 and 101.6% for TA98 and TA100, resp.) and, after further fractionation, four subfractions M8a, M8b, M8c, and M8d were obtained. Data from (1)H and (13)C NMR, and mass spectrometry analysis of fraction M8a (the one with the highest antimutagenic activity), suggest that the compound responsible for its antimutagenicity is an apocarotenoid.

Identifiers

PMID27006678
PMCPMC4783554

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.