Evidence map›Paper›PMID 27006520›Full record

ArticleActa histochemica et cytochemica2016

Expression of Sex Steroid Hormone Receptors in Vagal Motor Neurons Innervating the Trachea and Esophagus in Mouse.

Shigeyuki Mukudai, Ken Ichi Matsuda, Hideki Bando, Keiko Takanami, Takeshi Nishio, Yoichiro Sugiyama, Yasuo Hisa, Mitsuhiro Kawata

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta histochemica et cytochemica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Shigeyuki MukudaiDepartment of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine; Department of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kyoto 602-8566, Japan; Department of Otolaryngology-Bronchoesophagology, Kyoto Second Red Cross Hospital, Kamanza-Marutamachi, Kyoto 602-8026, Japan.
Ken Ichi MatsudaDepartment of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine.
Hideki BandoDepartment of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University of Medicine , Kawaramachi-Hirokoji, Kyoto 602-8566, Japan.
Keiko TakanamiDepartment of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine; Ushimado Marine Institute, Graduate School of Natural Science and Technology, Okayama University, Ushimado, Setouchi, Okayama 701-4303, Japan.
Takeshi NishioDepartment of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University of Medicine , Kawaramachi-Hirokoji, Kyoto 602-8566, Japan.
Yoichiro SugiyamaDepartment of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University of Medicine , Kawaramachi-Hirokoji, Kyoto 602-8566, Japan.
Yasuo HisaDepartment of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kyoto 602-8566, Japan; Faculty of Health and Medical Sciences, Kyoto Gakuen University, 18, Gotanda-cho, Yamanouchi, Kyoto 615-8577, Japan.
Mitsuhiro KawataDepartment of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine; School of Health Sciences, Bukkyo University, 7, Higashitoganoo-cho, Nishinokyo, Kyoto 604-8418, Japan.
Kyoto Prefectural University of Medicine · JPBukkyo University · JPMarine Institute · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The medullary vagal motor nuclei, the nucleus ambiguus (NA) and dorsal motor nucleus of the vagus (DMV), innervate the respiratory and gastrointestinal tracts. We conducted immunohistochemical analysis of expression of the androgen receptor (AR) and estrogen receptor α (ERα), in relation to innervation of the trachea and esophagus via vagal motor nuclei in mice. AR and ERα were expressed in the rostral NA and in part of the DMV. Tracing experiments using cholera toxin B subunit demonstrated that neurons of vagal motor nuclei that innervate the trachea and esophagus express AR and ERα. There was no difference in expression of sex steroid hormone receptors between trachea- and esophagus-innervating neurons. These results suggest that sex steroid hormones may act on vagal motor nuclei via their receptors, thereby regulating functions of the trachea and esophagus.

Indexed as

dorsal motor nucleus of the vagusesophagusnucleus ambiguussex hormone receptorstrachea

Identifiers

PMID27006520
PMCPMC4794553
OpenAlexW2343121290

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.