Evidence map›Paper›PMID 27006495›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2016

Neoantigen: A Long March toward Cancer Immunotherapy.

Yang Liu

Abstract readComment
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Yang LiuCenter for Cancer and Immunology Research, Children's Research Institute, Children's National Health System, and Department of Pediatrics, George Washington University School of Medicine, Washington, DC.

Funding

Checkpoints of Host Response to Cellular InjuriesR01AI064350 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIU, YANG, ZHENG, PAN · 2006 to 2019
$5.6M
Tumor burden and T cell immunityR01CA058033 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIU, YANG · 1992 to 2013
$3.3M
Targeted Elimination of Cancer Stem Cells for AML TherapyR01CA171972 · NCI · CHILDREN'S RESEARCH INSTITUTE · PI LIU, YANG, MALEK, SAMI NIMER · 2013 to 2017
$2.3M
Therapeutic Elimination of Stem Cells for Relapsed Pediatric AMLU01CA183030 · NCI · CHILDREN'S RESEARCH INSTITUTE · PI LIU, YANG, SCHORE, REUVEN J · 2014 to 2017
$2.3M
Human gene knock-in mice and anti-cancer antibodiesR41CA093107 · NCI · ONCOIMMUNE, LTD · PI LIU, YANG · 2001 to 2001
$165k
NCI NIH HHS R01 CA058033NCI NIH HHS R01 CA171972NCI NIH HHS R41 CA093107NCI NIH HHS U01 CA183030NIAID NIH HHS R01 AI064350
6 · The paper itself

Abstract

Somatic mutations in cancer give rise to neoantigens. Technology revolutions in cancer genomics and immunology have made it possible to rapidly identify neoantigens for cancer vaccines. Leisegang and colleagues report that it is practical to rapidly identify neoantigens for adoptive T-cell therapy in a mouse tumor model. Clin Cancer Res; 22(11); 2602-4. ©2016 AACRSee related article by Leisegang et al., p. 2734.

Indexed as

NeoplasmsPoint MutationAnimalsAntigens, NeoplasmGenetic TherapyImmunotherapyMiceReceptors, Antigen, T-CellAntigens, NeoplasmReceptors, Antigen, T-Cell

Identifiers

PMID27006495
PMCPMC4891220

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.