Evidence map›Paper›PMID 27006133›Full record

ReviewWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology2016

Nanoparticles and radiotracers: advances toward radionanomedicine.

Edwin C Pratt, Travis M Shaffer, Jan Grimm

Open access · greenAbstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
7.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Precision Oncology: Advances in Drug Delivery and Imaging.Recent advances in drug delivery and formulation · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Preclinical Voxel-Based Dosimetry in Theranostics: a Review.Nuclear medicine and molecular imaging · 2020
    Review
  16. Review
  17. Article
  18. Nanoparticles to mediate X-ray-induced photodynamic therapy and Cherenkov radiation photodynamic therapy.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2019
    Review
  19. Review
  20. Engineering molecular imaging strategies for regenerative medicine.Bioengineering & translational medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Edwin C PrattDepartment of Pharmacology, Weill Cornell Medical College, New York, NY, USA.
Travis M ShafferDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jan GrimmDepartment of Pharmacology, Weill Cornell Medical College, New York, NY, USA. grimmj@mskcc.org.
Memorial Sloan Kettering Cancer Center · USCornell University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Cerenkov luminescence imaging for image-guided cancer surgeryR01CA183953 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI GRIMM, JAN · 2015 to 2019
$2.6M
Cerenkov-emission based nanosensors to detect biologic activities in vivoR01EB014944 · NIBIB · SLOAN-KETTERING INST CAN RESEARCH · PI GRIMM, JAN · 2012 to 2015
$1.6M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA183953NIBIB NIH HHS R01 EB014944
6 · The paper itself

Abstract

In this study, we cover the convergence of radiochemistry for imaging and therapy with advances in nanoparticle (NP) design for biomedical applications. We first explore NP properties relevant for therapy and theranostics and emphasize the need for biocompatibility. We then explore radionuclide-imaging modalities such as positron emission tomography (PET), single-photon emission computed tomography (SPECT), and Cerenkov luminescence (CL) with examples utilizing radiolabeled NP for imaging. PET and SPECT have served as diagnostic workhorses in the clinic, while preclinical NP design examples of multimodal imaging with radiotracers show promise in imaging and therapy. CL expands the types of radionuclides beyond PET and SPECT tracers to include high-energy electrons (β

Indexed as

NanoparticlesRadiopharmaceuticalsTheranostic NanomedicineAnimalsHumansMicePositron-Emission TomographyTomography, Emission-Computed, Single-PhotonRadiopharmaceuticals

Identifiers

PMID27006133
PMCPMC5035177
OpenAlexW2306459148

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.