ArticleBMC pregnancy and childbirth2016
Increased prevalence of some birth defects in Korea, 2009-2010.
Article in BMC pregnancy and childbirth, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and associated factors of birth defects among newborns in sub-Saharan African countries: a systematic review and meta-analysis.The Pan African medical journal · 2020Pooled it
- The burden of neural tube defects in Southern Ethiopia: trends, hotspots, and public health implications.PeerJ · 2026Article
- Birth prevalence and associated factors of congenital anomalies among neonates born at a public hospital in Awi Zone, Northwestern Ethiopia: institutional based cross-sectional study.BMC pediatrics · 2025Article
- Pregnancy and neonatal outcomes after fetal exposure to statins among women with dyslipidemia: a nationwide cohort.European journal of pediatrics · 2025Article
- Folic acid supplementation on congenital heart disease and its dual character.Current research in pharmacology and drug discovery · 2025Review
- Temporal trends in the prevalence of major birth defects in China: a nationwide population-based study from 2007 to 2021.World journal of pediatrics : WJP · 2024Article
- Maternal periconceptional folic acid supplementation and risk for fetal congenital genitourinary system defects.Pediatric research · 2024Article
- Major Congenital Anomalies in Korean Livebirths in 2013-2014: Based on the National Health Insurance Database.Journal of Korean medical science · 2023Article
- Prevalence of congenital anomalies and related factors in live births in Zahedan, Southeast of Iran: A cross-sectional study.International journal of reproductive biomedicine · 2023Article
- The trend of marriage, childbearing, and divorce and its determinants of socio-economic factors on divorce in Yazd province 2016-2021: A cross-sectional study.International journal of reproductive biomedicine · 2023Article
- Prenatal diagnosis of Sex determining region Y -box transcription factor 2 anophthalmia syndrome caused by germline mosaicism using next-generation sequencing: A case report.International journal of reproductive biomedicine · 2023Article
- Willingness to Pay for Down Syndrome Screening: A systematics Review.Medical journal of the Islamic Republic of Iran · 2022Review
- Ten-year trends in the incidence of microtia: a nationwide population-based study from Taiwan.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021Article
- Prevalence and Trends of Congenital Anomalies Among Neonates at Jimma Medical Center, Jimma, Ethiopia: A Three-Year Retrospective Study.Pediatric health, medicine and therapeutics · 2021Article
- Article
- A hospital-based birth defects surveillance system in Kampala, Uganda.BMC pregnancy and childbirth · 2019Article
- Prevalence, types, and malformations in congenital anomalies of the kidney and urinary tract in newborns: a retrospective hospital-based study.Italian journal of pediatrics · 2019Article
- Epidemiology of birth defects based on surveillance data from 2011-2015 in Guangxi, China: comparison across five major ethnic groups.BMC public health · 2018Article
- Trends in the Prevalences of Selected Birth Defects in Korea (2008⁻2014).International journal of environmental research and public health · 2018Article
- Lumbosacral Defects in a 16th-18th-Century Joseon Dynasty Skeletal Series from Korea.BioMed research international · 2018Article
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7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBirth defects are a leading cause of neonatal and infant mortality, and several studies have indicated an increase in the prevalence of birth defects; more recent investigations have suggested that the trends of some defects are increasing in rapidly industrialized areas. This study estimates the prevalence rate and types of birth defects in Korea.
methodsThis study used medical insurance benefit data of 403,250 infants aged less than one year from the National Health Insurance Corporation from seven metropolitan areas in Korea for 2009 and 2010.
resultsThe prevalence rate of birth defects was 548.3 per 10,000 births (95% CI: 541.1-555.6), 306.8 among boys and 241.5 among girls. Anomalies of the circulatory system (particularly septal defects) were the most common (180.8 per 10,000), followed by defects of the genitourinary tract (130.1 per 10,000) (particularly obstructive genitourinary and undescended testis), musculoskeletal system (105.7 per 10,000), digestive system (24.7 per 10,000), and central nervous system (15.6 per 10,000).
conclusionsRelatively higher rates of some birth defects were found in the metropolitan areas. The high differences of birth prevalences for septal heart defects and undescended testis are probably due in part to progress in clinical management and more frequent prenatal diagnosis. Environmental exposure might play a critical role in the development of some birth defects. In attempting to describe the prevalence and spatio-temporal variations of birth defects in Korea, establishment of a registry system of birth defects and environmental surveillance are needed.
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