Evidence map›Paper›PMID 27005804›Full record

ReviewCurrent atherosclerosis reports2016

Cardiorespiratory Fitness and Atherosclerosis: Recent Data and Future Directions.

Emile Mehanna, Anne Hamik, Richard A Josephson

Abstract readReview
In one paragraph

Review in Current atherosclerosis reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emile MehannaDivision of Cardiovascular Medicine, Harrington Heart & Vascular Institute, University Hospitals Health System, Mailstop LKS 5038, 11100 Euclid Avenue, Cleveland, OH, 44106-5038, USA.
Anne HamikDivision of Cardiovascular Medicine, Harrington Heart & Vascular Institute, University Hospitals Health System, Mailstop LKS 5038, 11100 Euclid Avenue, Cleveland, OH, 44106-5038, USA.
Richard A JosephsonDivision of Cardiovascular Medicine, Harrington Heart & Vascular Institute, University Hospitals Health System, Mailstop LKS 5038, 11100 Euclid Avenue, Cleveland, OH, 44106-5038, USA. richard.josephson@uhhospitals.org.

Funding

KLF4 and Transcriptional Control of NeovascularizationR01HL113570 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI HAMIK, ANNE · 2013 to 2017
$1.9M
NHLBI NIH HHS HL113570NHLBI NIH HHS R01 HL113570
6 · The paper itself

Abstract

Historically, the relationship between exercise and the cardiovascular system was viewed as unidirectional, with a disease resulting in exercise limitation and hazard. This article reviews and explores the bidirectional nature, delineating the effects, generally positive, on the cardiovascular system and atherosclerosis. Exercise augments eNOS, affects redox potential, and favorably affects mediators of atherosclerosis including lipids, glucose homeostasis, and inflammation. There are direct effects on the vasculature as well as indirect benefits related to exercise-induced changes in body composition and skeletal muscle. Application of aerobic exercise to specific populations is described, with the hope that this knowledge will move the science forward and improve individual patient outcome.

Indexed as

Cardiovascular SystemPhysical FitnessAtherosclerosisBody CompositionCardiovascular DiseasesExerciseHumansCardiac rehabilitationCardiorespiratory fitnessCardiovascular disease preventioneNOSExercise

Identifiers

PMID27005804
PMCPMC5593139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.