ArticleOrganic & biomolecular chemistry2016
Synthesis of highly functionalized oligobenzamide proteomimetic foldamers by late stage introduction of sensitive groups.
Article in Organic & biomolecular chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Understanding p300-transcription factor interactions using sequence variation and hybridization.RSC chemical biology · 2022Article
- Bis(2-methyl-pyridinium) tetra-chlorido-cuprate(II): synthesis, structure and Hirshfeld surface analysis.Acta crystallographica. Section E, Crystallographic communications · 2021Article
- A catalytic protein-proteomimetic complex: using aromatic oligoamide foldamers as activators of RNase S.Chemical science · 2019Article
- Hypoxia inducible factor (HIF) as a model for studying inhibition of protein-protein interactions.Chemical science · 2017Article
- Hypoxia inducible factor down-regulation, cancer and cancer stem cells (CSCs): ongoing success stories.MedChemComm · 2017Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
α-Helix proteomimetics represent an emerging class of ligands that can be used to inhibit an array of helix mediated protein-protein interactions. Within this class of inhibitor, aromatic oligobenzamide foldamers have been widely and successfully used. This manuscript describes alternative syntheses of these compounds that can be used to access mimetics that are challenging to synthesize using previously described methodologies, permitting access to compounds functionalized with multiple sensitive side chains and accelerated library assembly through late stage derivatisation.
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Registered trials
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