SynthesisScientific reports2016
The Efficacy and Safety of Knotless Barbed Sutures in the Surgical Field: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Synthesis in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07507409 (Innovative Sternal Closure Techniques), which is not on this map. Cited by 26 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Innovative Sternal Closure Techniques: Evaluating STRATAFIX™ and DERMABOND™ for Reduced Complications in CABG Patients
Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Efficacy of laparoscopic barbed sutures in the repair of gastroduodenal perforations: a meta-analysis.BMC gastroenterology · 2026Pooled it
- Incidence and outcome characteristics of adverse event in surgery: an assessment based on systematic reviews of barbed suture.BMC medical research methodology · 2025Pooled it
- The Effectiveness and Safety of Barbed Sutures in the Bariatric Surgery: a Systematic Review and Meta-analysis.Obesity surgery · 2019Pooled it
- The efficacy and safety of knotless barbed sutures in total joint arthroplasty: a meta-analysis of randomized-controlled trials.Archives of orthopaedic and trauma surgery · 2018Pooled it
- Determinants of residual myometrial thickness after cesarean delivery: Comparative analysis of barbed versus conventional sutures-A sub-analysis from the SPIRAL trial.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Trial
- Barbed suture in neck dissection: a randomized clinical study on efficacy, safety and aesthetic outcome.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Trial
- Anterolateral advancement pharyngoplasty versus barbed reposition pharyngoplasty in patients with obstructive sleep apnea.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Trial
- Materiovigilance of unidirectional barbed and poliglecaprone 25 nonbarbed sutures used for intraoral incision closure: An open-label prospective study.Indian journal of pharmacologyTrial
- Traction method with pulley maneuver in minimally invasive hepatobiliary pancreatic surgery: how I do it differently?Surgical endoscopy · 2026Article
- Objective assessment of cesarean section suturing techniques using a uterine simulator.Scientific reports · 2026Article
- Article
- Knotless backstitching provides comparable strength to conventional knotting in porcine stomach suture biomechanics.Scientific reports · 2025Article
- Barbed Suture for Pancreaticojejunal Anastomosis: An Ally Against Pancreatic Fistula.Journal of surgical oncology · 2025Article
- The current role of barbed sutures in fascial closure of ventral hernia repair: a multicenter study using the abdominal core health quality collaborative database.Surgical endoscopy · 2024Article
- Catastrophic complications of a robot-assisted laparoscopic sacrocolpopexy with a barbed suture: ischaemic bowel.Journal of surgical case reports · 2024Article
- Postoperative small intestinal obstruction caused by barbed suture after robot-assisted laparoscopic sacrocolpopexy.IJU case reports · 2024Article
- Does Unidirectional Polyglycolide Caprolactone Barbed Suture Have Improved Outcomes Over Non-barbed Suture When Applied for Intra-oral Incision Closure?Journal of maxillofacial and oral surgery · 2024Article
- Article
- A Review of Barbed Sutures-Evolution, Applications and Clinical Significance.Bioengineering (Basel, Switzerland) · 2023Review
- Generation of Cross-Specialty Consensus Statements on Soft Tissue Management via a Modified Delphi Method.World journal of surgery · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The knotless barbed suture is an innovative type of suture that can accelerate the placement of sutures and eliminate knot tying. However, the outcomes of previous studies are still confounding. This study reviewed the application of different types of barbed sutures in different surgeries. We searched PubMed, EMBASE, CENTRAL and ClinicalTrials.gov to identify randomized controlled trials (RCTs) addressing the application of barbed sutures up to Feb. 2015. Two reviewers independently screened the literature and assessed the risk of bias of included studies. Then meta-analysis was performed using RevMan 5.3 software. Sensitivity analysis and subgroup analysis was performed. Seventeen RCTs (low to moderate risk of bias) involving 1992 patients were included. Compared with conventional sutures, the barbed suture could reduce suture time (SMD=-0.95, 95%CI -1.43 to -0.46, P = 0.0001) and the operative time (SMD=-0.28, 95%CI -0.46 to -0.10, P = 0.003), not significantly increase the estimated blood loss (SMD=-0.09, 95%CI -0.52 to 0.35, P = 0.70), but could lead to more postoperative complications (OR = 1.43, 95%CI 1.05 to 1.96, P = 0.03), These results varied in subgroups. Thus, barbed sutures are effective in reducing the suture and operative time, but the safety evidences are still not sufficient. It need be evaluated based on special surgeries and suture types before put into clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.