Evidence map›Paper›PMID 27005657›Full record

ArticleNutrients2016

Vitamin Status among Breastfed Infants in Bhaktapur, Nepal.

Manjeswori Ulak, Ram K Chandyo, Andrew L Thorne-Lyman, Sigrun Henjum, Per M Ueland, Øivind Midttun, Prakash S Shrestha, Wafaie W Fawzi, Lauren Graybill, Tor A Strand

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Manjeswori UlakDepartment of Child Health, Institute of Medicine, Tribhuvan University, Maharajgunj, P.O. Box 1524, Kathmandu 44600, Nepal. manjeswori@gmail.com.
Ram K ChandyoCentre for International Health, University of Bergen, P.O. Box 7800, 5020 Bergen, Norway. ram.chandyo@uib.no.
Andrew L Thorne-LymanDepartment of Nutrition, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA. a.thorne-lyman@cgiar.org.
Sigrun HenjumOslo and Akershus University College of Applied Sciences, P.O. Box 4, St. Olavs plass, 0130 Oslo, Norway. sigrun.henjum@hioa.no.
Per M UelandSection for Pharmacology, Department of Clinical Science, University of Bergen, 5020 Bergen, Norway. per.ueland@ikb.uib.no.
Øivind MidttunBevital AS, c/o Helse Bergen, Jonas Lies veg 87, 5020 Bergen, Norway. bjorn.midttun@uib.no.
Prakash S ShresthaDepartment of Child Health, Institute of Medicine, Tribhuvan University, Maharajgunj, P.O. Box 1524, Kathmandu 44600, Nepal. prakashsunder@hotmail.com.
Wafaie W FawziDepartment of Nutrition, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA. mina@hsph.harvard.edu.
Lauren GraybillDepartment of Epidemiology and Global Health and Population, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA. lag111@mail.harvard.edu.
Tor A StrandCentre for International Health, University of Bergen, P.O. Box 7800, 5020 Bergen, Norway. tor.strand@uib.no.
Harvard University · USTribhuvan University Teaching Hospital · NPUniversity of Bergen · NOBevital (Norway) · NOInnlandet Hospital Trust · NOOsloMet – Oslo Metropolitan University · NO

Funding

Training Program in Reproductive, Perinatal, and Pediatric EpidemiologyT32HD052468 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Julie L Daniels · 2008 to 2026
$3.8M
NICHD NIH HHS T32 HD052468
6 · The paper itself

Abstract

Vitamin deficiencies are known to be common among infants residing in low- and middle-income countries but relatively few studies have assessed several biochemical parameters simultaneously. The objective of the study was to describe the status of vitamins (A, D, E, B₆, B12 and folate) in breastfed infants. We measured the plasma concentrations of trans retinol, 25 hydroxy vitamin D, α-tocopherol, pyridoxal 5'-phosphate, cobalamin, folate, methylmalonic acid, homocysteine, hemoglobin and C-reactive protein from 467 randomly selected infants. One in five (22%) was deficient in at least one vitamin. Mean (SD) plasma folate concentration was 73 (35) nmol/L, and no infant in the sample was folate deficient. Vitamin B₆ deficiency and vitamin B12 deficiency was found in 22% and 17% of the infants, respectively. Elevated plasma methylmalonic acid or total homocysteine concentration was found in 82% and 62% of infants, respectively. Fifteen percent of infants were vitamin A deficient and 65% were marginally deficient in vitamin A. Fewer than 5% of infants had low plasma vitamin D concentration or vitamin E concentration (α-tocopherol <9.3 µmol/L). Our results illustrate the importance of continued supplementation campaigns and support the expansion of food fortification and dietary diversification programs that target children and women in Nepal.

Indexed as

Breast FeedingInfant Nutritional Physiological PhenomenaNutritional StatusAdultAge FactorsAvitaminosisBiomarkersDietary SupplementsFemaleFood, FortifiedHealth SurveysHumansInfantMaleNepalNutrition AssessmentBiomarkersVitaminshomocysteineinfantmethylmalonic acidNepalvitamins

Identifiers

PMID27005657
PMCPMC4808878
OpenAlexW2296578180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.