Evidence map›Paper›PMID 27005444›Full record

ReviewTrends in genetics : TIG2016

New Insights into the Regulation of Heterochromatin.

Jiyong Wang, Sharon T Jia, Songtao Jia

Abstract readReview
In one paragraph

Review in Trends in genetics : TIG, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed.

  1. Article
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  9. The 80Journal of microbiology and biotechnology · 2024
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  15. Canonical and non-canonical functions of STAT in germline stem cell maintenance.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiyong WangDepartment of Biological Sciences, Columbia University, New York, NY, USA.
Sharon T JiaDepartment of Biological Sciences, Columbia University, New York, NY, USA.
Songtao JiaDepartment of Biological Sciences, Columbia University, New York, NY, USA. Electronic address: jia@biology.columbia.edu.

Funding

Mechanism of heterochromatin assemblyR01GM085145 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI JIA, SONGTAO · 2008 to 2017
$3.0M
NIGMS NIH HHS R01 GM085145
6 · The paper itself

Abstract

All living organisms are constantly exposed to stresses from internal biological processes and surrounding environments, which induce many adaptive changes in cellular physiology and gene expression programs. Unexpectedly, constitutive heterochromatin, which is generally associated with the stable maintenance of gene silencing, is also dynamically regulated in response to stimuli. In this review we discuss the mechanism of constitutive heterochromatin assembly, its dynamic nature, and its responses to environmental changes.

Indexed as

Gene-Environment InteractionTranscription, GeneticChromatin Assembly and DisassemblyGene Expression RegulationGene SilencingHeterochromatinHistonesHumansHeterochromatinHistonesconstitutive heterochromatindynamicsepigenetic adaptationstress

Identifiers

PMID27005444
PMCPMC4842111

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.