Evidence map›Paper›PMID 27004707›Full record

ArticleAnatolian journal of cardiology2016

Evaluating functional capacity, and mortality effects in the presence of atrial electromechanical conduction delay in patients with systolic heart failure.

Murat Bilgin, Bekir Serhat Yıldız, Kamil Tülüce, İlker Gül, Mustafa Beyazıt Alkan, Ahmet Sayın, Aysel İslamlı, Tolga Han Efe, Yusuf İzzettin Alihanoğlu, Mehdi Zoghi and 1 more

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Article in Anatolian journal of cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Murat BilginDepartment of Cardiology, Ankara Dışkapı Training and Research Hospital, Ankara-Turkey. drbilginmurat@hotmail.com.
Bekir Serhat YıldızDepartment of Cardiology, Faculty of Medicine, Pamukkale University, Denizli-Turkey.
Kamil TülüceDepartment of Cardiology, İzmir Karşıyaka State Hospital, İzmir-Turkey.
İlker GülDepartment of Cardiology, Faculty of Medicine, İzmir Şifa University, İzmir-Turkey.
Mustafa Beyazıt AlkanDepartment of Cardiology, Faculty of Medicine, Ege University, İzmir-Turkey.
Ahmet SayınDepartment of Cardiology, İzmir Tepecik Training and Research Hospital, İzmir-Turkey.
Aysel İslamlıDepartment of Cardiology, Faculty of Medicine, Ege University, İzmir-Turkey.
Tolga Han EfeDepartment of Cardiology, Ankara Dışkapı Training and Research Hospital, Ankara-Turkey.
Yusuf İzzettin AlihanoğluDepartment of Cardiology, Faculty of Medicine, Pamukkale University, Denizli-Turkey.
Mehdi ZoghiDepartment of Cardiology, Faculty of Medicine, Ege University, İzmir-Turkey.
Mustafa AkınDepartment of Cardiology, Faculty of Medicine, Ege University, İzmir-Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAtrial functions are relatively suppressed in heart failure (HF). We aimed to investigate the associations of intra- and inter-atrial electromechanical conduction delay (EMCD) with functional class and mortality over a 12-month follow-up period.

methodsThe prospective study included 65 patients with systolic HF and 65 healthy subjects with normal sinus rhythm. Left ventricular (LV) systolic functions and left atrial (LA) dimensions and volumes were evaluated by transthoracic echocardiography. Tissue Doppler imaging (TDI) signals at the lateral border of the mitral annulus (lateral PA'), septal mitral annulus (septal PA'), and tricuspid annulus (tricuspid PA') were measured. Intra- and inter-atrial EMCD were calculated.

resultsMitral inflow velocities were studied using pulsed-wave Doppler after placing the sample volume at the leaflets' tips. The peak early (E wave) and late (A wave) velocities were measured. The septal annular E/E' ratio was relatively higher and lateral, septal, and right ventricular S, E', and A' waves were significantly lower in the HF group than in the control group (12.49±6.03 - 7.16±1.75, pE/E' <0.0001). Intra-atrial EMCD was detected as 117.5 ms and inter-atrial EMCD as 127.5 ms in patients with prolonged atrial EMCD. A significant increase was found in prolonged intraand inter-atrial EMCD according to functional capacity increase (p=0.012 and p=0.031, respectively). The incidence of mortality was significantly higher in patients with prolonged atrial EMCD (p=0.025), and 5 patients in the HF group died during the study over the 12-month follow-up period.

conclusionsIn this study, we found a relationship between prolonged atrial conduction time and increased functional class and mortality in patients with systolic HF.

Identifiers

PMID27004707
PMCPMC5368513

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.