Evidence map›Paper›PMID 27004247›Full record

ArticleEndoscopy international open2016

Biodegradable stents for the treatment of bowel strictures in Crohn's disease: technical results and challenges.

John Gásdal Karstensen, Katrine Risager Christensen, Jørn Brynskov, Claus Rønholt, Peter Vilmann, Jakob Hendel

Open access · goldAbstract readCase Reports
In one paragraph

Article in Endoscopy international open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Futuristic Developments and Applications in Endoluminal Stenting.Gastroenterology research and practice · 2022
    Review
  9. Review
  10. Review
  11. Endoscopic management of Crohn's strictures.World journal of gastroenterology · 2018
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

John Gásdal KarstensenGastro Unit, Division of Endoscopy, Copenhagen University Hospital Herlev, Denmark; Gastro Unit, Division of Surgery, Copenhagen University Hospital Hvidovre, Denmark.
Katrine Risager ChristensenGastro Unit, Division of Endoscopy, Copenhagen University Hospital Herlev, Denmark.
Jørn BrynskovGastro Unit, Division of Endoscopy, Copenhagen University Hospital Herlev, Denmark.
Claus RønholtGastro Unit, Division of Surgery, Copenhagen University Hospital Herlev, Denmark.
Peter VilmannGastro Unit, Division of Endoscopy, Copenhagen University Hospital Herlev, Denmark.
Jakob HendelGastro Unit, Division of Endoscopy, Copenhagen University Hospital Herlev, Denmark.
Copenhagen University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND STUDY

aimsIn patients with Crohn's disease, the idea of biodegradable stents for treatment of bowel strictures with limited effect of endoscopic balloon dilation is tempting and initial results have been promising. The aim of this study was to evaluate the technical and clinical success of biodegradable stents for treatment of inflamed Crohn's strictures refractory to endoscopic balloon dilatation. PATIENTS AND

methodsConsecutive patients treated with biodegradable stents due to Crohn's disease and inflamed bowel strictures refractory to endoscopic balloon dilatation were included. Technical and clinical success were evaluated.

resultsSix patients were included in the study. Technical success was obtained in five patients (83 %). Clinical success was limited to one patient (20 %); failure was observed due to mucosal overgrowth (n = 2), stent migration (n = 1), and stent collapse (n = 1).

conclusionsIn Crohn's disease, it is technically feasible to treat bowel strictures with biodegradable stents. However, we have stopped using biodegradable stents due to lack of clinical success and side effects such as mucosal overgrowth and stent collapse.

Identifiers

PMID27004247
PMCPMC4798842
OpenAlexW2299999120

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.