ReviewInternational journal of health sciences2016
Molecular Genetic of Atopic dermatitis: An Update.
Review in International journal of health sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Abrocitinib, tralokinumab and upadacitinib for treating moderate-to-severe atopic dermatitis.Health technology assessment (Winchester, England) · 2024Pooled it
- Integrative transcriptome-wide analysis of atopic dermatitis for drug repositioning.Communications biology · 2022Pooled it
- Genetic profiling of patients with atopic dermatitis reveals immune and skin barrier variants associated with generalized eczema and optimal response to Dupilumab therapy.Frontiers in immunology · 2026Article
- Ethnic and Racial Disparities in Clinical Manifestations of Atopic Dermatitis.Archives of internal medicine research · 2024Article
- Fatty Acids Profile and the Relevance of Membranes as the Target of Nutrition-Based Strategies in Atopic Dermatitis: A Narrative Review.Nutrients · 2023Review
- Environmental Exposures may Hold the Key; Impact of Air Pollution, Greenness, and Rural/Farm Lifestyle on Allergic Outcomes.Current allergy and asthma reports · 2023Review
- Association ofFrontiers in pediatrics · 2023Article
- Increased Expression of Toll-Like Receptor (TLR) 2 and TLR6 on Peripheral Blood Monocytes by Induction of Staphylococcal Enterotoxin B During Exacerbation of Atopic Dermatitis Patients.Clinical, cosmetic and investigational dermatology · 2023Article
- Atopic Dermatitis With Coexisting Food Allergy in Early Life Is Associated With Childhood Asthma.Allergy, asthma & immunology research · 2022Article
- Potential of Tamanu (Evidence-based complementary and alternative medicine : eCAM · 2021Review
- The Role of Environmental Exposures in Atopic Dermatitis.Current allergy and asthma reports · 2020Review
- Disease Mechanisms in Atopic Dermatitis: A Review of Aetiological Factors.Acta dermato-venereologica · 2020Review
- Genetics in Atopic Dermatitis: Historical Perspective and Future Prospects.Acta dermato-venereologica · 2020Review
- Epidemiology, Diagnosis, and Treatment of Atopic Dermatitis in the Developing Countries of Asia, Africa, Latin America, and the Middle East: A Review.Dermatology and therapy · 2019Review
- Microbiota and Immune-Mediated Skin Diseases-An Overview.Microorganisms · 2019Review
- Personalized medicine-concepts, technologies, and applications in inflammatory skin diseases.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2019Review
- Susceptible loci associated with autoimmune disease as potential biomarkers for checkpoint inhibitor-induced immune-related adverse events.ESMO open · 2019Review
- Markers of atopic dermatitis, allergic rhinitis and bronchial asthma in pediatric patients: correlation with filaggrin, eosinophil major basic protein and immunoglobulin E.Clinical and molecular allergy : CMA · 2018Article
- Lowering relative humidity level increases epidermal protein deimination and drives human filaggrin breakdown.Journal of dermatological science · 2017Article
- Association of Moderate-Severe Atopic Dermatitis with Dental Anomalies.Indian journal of dermatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atopic dermatitis (AD) is a chronic multifactorial inflammatory skin disease. The pathogenesis of AD remains unclear, but the disease results from dysfunctions of skin barrier and immune response, where both genetic and environmental factors play a key role. Recent studies demonstrate the substantial evidences that show a strong genetic association with AD. As for example, AD patients have a positive family history and have a concordance rate in twins. Moreover, several candidate genes have now been suspected that play a central role in the genetic background of AD. In last decade advanced procedures similar to genome-wide association (GWA) and single nucleotide polymorphism (SNP) have been applied on different population and now it has been clarified that AD is significantly associated with genes of innate/adaptive immune systems, human leukocyte antigens (HLA), cytokines, chemokines, drug-metabolizing genes or various other genes. In this review, we will highlight the recent advancements in the molecular genetics of AD, especially on possible functional relevance of genetic variants discovered to date.
Indexed as
Identifiers
27004062PMC4791162W2290401041What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.