Evidence map›Paper›PMID 27003990›Full record

ReviewWorld journal of gastroenterology2016

Evidence-based medical oncology and interventional radiology paradigms for liver-dominant colorectal cancer metastases.

Alan Alper Sag, Fatih Selcukbiricik, Nil Molinas Mandel

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Bioinformatic Analysis of the Effect of theBioMed research international · 2022
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Molecular Pathways: Targeting the Microenvironment of Liver Metastases.Clinical cancer research : an official journal of the American Association for Cancer Research · 2017
    Review
  15. Review
  16. Article
  17. Colorectal cancer in young adults: A difficult challenge.World journal of gastroenterology · 2017
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Alan Alper SagAlan Alper Sag, Division of Interventional Radiology, Department of Radiology, Koc University School of Medicine, Istanbul 34450, Turkey.
Fatih SelcukbiricikAlan Alper Sag, Division of Interventional Radiology, Department of Radiology, Koc University School of Medicine, Istanbul 34450, Turkey.
Nil Molinas MandelAlan Alper Sag, Division of Interventional Radiology, Department of Radiology, Koc University School of Medicine, Istanbul 34450, Turkey.
Koç University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer metastasizes predictably, with liver predominance in most cases. Because liver involvement has been shown to be a major determinant of survival in this population, liver-directed therapies are increasingly considered even in cases where there is (limited) extrahepatic disease. Unfortunately, these patients carry a known risk of recurrence in the liver regardless of initial therapy choice. Therefore, there is a demand for minimally invasive, non-surgical, personalized cancer treatments to preserve quality of life in the induction, consolidation, and maintenance phases of cancer therapy. This report aims to review evidence-based conceptual, pharmacological, and technological paradigm shifts in parenteral and percutaneous treatment strategies as well as forthcoming evidence regarding next-generation systemic, locoregional, and local treatment approaches for this patient population.

Indexed as

Evidence-Based MedicineMedical OncologyRadiology, InterventionalAblation TechniquesAntineoplastic Combined Chemotherapy ProtocolsChemoembolization, TherapeuticChemotherapy, AdjuvantColorectal NeoplasmsHumansImmunotherapyLiver NeoplasmsNeoplasm StagingRadiography, InterventionalTreatment OutcomeAntineoplastic agentsChemoembolizationColonic neoplasmsFOLFOX protocolImmunotherapyIrinotecan, 5-flurouracil, and leucovorin protocolMicrowave ablationNeoplasm metastasisRadiofrequency ablationRectal neoplasmsTherapeutic

Identifiers

PMID27003990
PMCPMC4789988
OpenAlexW2329908807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.