ArticleSoft matter2016
Lateral pressure-mediated protein partitioning into liquid-ordered/liquid-disordered domains.
Article in Soft matter, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Inside the membrane: a closer look using elastic scattering techniques and friends.European biophysics journal : EBJ · 2026Review
- The Importance of Bilayer Asymmetry in Biological Membranes: Insights from Model Membranes.Membranes · 2025Review
- Allosteric modulation of integral protein activity by differential stress in asymmetric membranes.PNAS nexus · 2023Article
- Modifications of Plasma Membrane Organization in Cancer Cells for Targeted Therapy.Molecules (Basel, Switzerland) · 2021Review
- Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape.Nature chemical biology · 2020Article
- Membrane Protein Structures in Lipid Bilayers; Small-Angle Neutron Scattering With Contrast-Matched Bicontinuous Cubic Phases.Frontiers in chemistry · 2020Article
- Global small-angle scattering data analysis of inverted hexagonal phases.Journal of applied crystallography · 2019Article
- Complex biomembrane mimetics on the sub-nanometer scale.Biophysical reviews · 2017Review
- The non-bilayer lipid MGDG stabilizes the major light-harvesting complex (LHCII) against unfolding.Scientific reports · 2017Article
- Nonadditive Compositional Curvature Energetics of Lipid Bilayers.Physical review letters · 2016Article
- Subnanometer Structure of an Asymmetric Model Membrane: Interleaflet Coupling Influences Domain Properties.Langmuir : the ACS journal of surfaces and colloids · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
We have studied the contributions of stored elastic energies in liquid-ordered (Lo) and liquid-disordered (Ld) domains to transmembrane proteins using the lateral pressure concept. In particular we applied previously reported experimental data for the membrane thickness, intrinsic curvature and bending elasticities of coexisting Lo/Ld domains to calculate whether proteins of simple geometric shapes would preferentially diffuse into Lo or Ld domains and form oligomers of a certain size. For the studied lipid mixture we generally found that proteins with convex shapes prefer sorting to Ld phases and the formation of large clusters. Lo domains in turn would be enriched in monomers of concave shaped proteins. We further observed that proteins which are symmetric with respect to the bilayer center prefer symmetric Lo or Ld domains, while asymmetric proteins favor a location in domains with Lo/Ld asymmetry. In the latter case we additionally retrieved a strong dependence on protein directionality, thus providing a mechanism for transmembrane protein orientation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.